![L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]- structure, CAS 159857-81-5](/structures/210000/188174_1_159857_81_5.png)
CAS Number159857-81-5
Synonymsmaleimidocaproyl-val-Cit-PAB-OCOpNP; maleimido-caproyl-valine-citrulline-para-aminobenzyl-4-nitrophenylcarbonate; MC-VAL-CIT-PAB-PNB; Mc-Val-Cit-PABC-PNP
Molecular FormulaC35H43N7O11
Molecular Weight737.76
Density1.3±0.1 g/cm3
Boiling Point1034.5±65.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 159857-81-5 |
| Catalog No. | 2A-3186844 |
| Chinese Name | MC-Val-Cit-PABC-PNP |
| Synonyms | maleimidocaproyl-val-Cit-PAB-OCOpNP; maleimido-caproyl-valine-citrulline-para-aminobenzyl-4-nitrophenylcarbonate; MC-VAL-CIT-PAB-PNB; Mc-Val-Cit-PABC-PNP |
| Molecular Formula | C35H43N7O11 |
| Molecular Weight | 737.76 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 1034.5±65.0 °C at 760 mmHg |
| Storage Condition | 2~8℃ |
| Application | Mc-Val-Cit-PABC-PNP is a cleavable cathepsin linker for the synthesis of antibody-drug conjugates (ADCs). |
| PubChem ID | 468592337 |
| MDL Number | MFCD22200431 |
| InChI | InChI=1S/C35H43N7O11/c1-22(2)31(40-28(43)8-4-3-5-20-41-29(44)17-18-30(41)45)33(47)39-27(7-6-19-37-34(36)48)32(46)38-24-11-9-23(10-12-24)21-52-35(49)53-26-15-13-25(14-16-26)42(50)51/h9-18,22,27,31H,3-8,19-21H2,1-2H3,(H,38,46)(H,39,47)(H,40,43)(H3,36,37,48)/t27-,31-/m0/s1 |
| InChI Key | HYSPJPGXSALJRR-DHIFEGFHSA-N |
| Beilstein/REAXYS | 10322169 |
| NACRES Code | NA.22 |
| UNSPSC | 12352200 |
| Transport Info | Product Name: Mc-Val-Cit-PABC-PNP |
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