CAS Number110-16-7
Synonyms(2Z)-2-Butenedioic acid; cis-2-Butenedioic Acid; 2-Butenedioicacid (2Z)-; MFCD00063177; EINECS 203-742-5; Maleic acid; cis-Butenedioic acid,Toxilic acid; Maleic acid [NA2215]; (2Z)-But-2-enedioic acid
Molecular FormulaC4H4O4
Molecular Weight116.072
Purity98.00%
Density1.5±0.1 g/cm3
Boiling Point355.5±25.0 °C at 760 mmHg
Melting Point134-138ºC
Appearancewhite solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 110-16-7 |
| Catalog No. | 2A-9018723 |
| Chinese Name | 马来酸 |
| Synonyms | (2Z)-2-Butenedioic acid; cis-2-Butenedioic Acid; 2-Butenedioicacid (2Z)-; MFCD00063177; EINECS 203-742-5; Maleic acid; cis-Butenedioic acid,Toxilic acid; Maleic acid [NA2215]; (2Z)-But-2-enedioic acid |
| Molecular Formula | C4H4O4 |
| Molecular Weight | 116.072 |
| Purity | 98.00 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 355.5±25.0 °C at 760 mmHg |
| Melting Point | 134-138ºC |
| Appearance | white solid |
| Water Solubility | 790 g/L (25 ºC) |
| Storage Condition | 1. Store in a cool, ventilated warehouse. Keep awa |
| Packaging | III |
| Application | Maleic Acid inhibits glutamate decarboxylase (GAD) in Escherichia coli (E. coli) and Listeria (L. monocytogenes). |
| HTC | 2917190090 |
| SMILES | O=C(O)C=CC(=O)O |
| InChI | InChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+ |
| InChI Key | VZCYOOQTPOCHFL-UPHRSURJSA-N |
| MSDS | msds/18723_2_110_16_7.pdf |
| Bioactivity | Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Infection Target Human Endogenous Metabolite GAD In Vitro The MICs of WT 10403S for the acids (e.g., Maleic Acid) are 34 mM, 25 mM, 31 mM and 30 mM which correspond to pH values prior to growth of 4.84, 5.14, 5.32 and 5.02 respectively. Of all compounds tested, Maleic Acid is the least inhibitory despite acting at a lower pH (4.84). The most acid resistant (10403S) and the weakest (EGD-e) strain are challenged with 8.6 mM and 4.3 mM of each organic acid at pH 3 and 3.3 respectively. On both strains, Maleic Acid is the most bactericidal[2]. References [1]. Fonda ML, et al. Glutamate decarboxylase. Substrate specificity and inhibition by carboxylic acids. Biochemistry. 1972 Mar 28;11(7):1304-9. [2]. Paudyal R, et al. A novel approach in acidic disinfection through inhibition of acid resistance mechanisms; Maleic acid-mediated inhibition of glutamate decarboxylase activity enhances acid sensitivity of Listeria monocytogenes. Food Microbiol. 2018 Feb;69:96-104. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 355.5±25.0 °C at 760 mmHg Melting Point 134-138ºC Molecular Formula C4H4O4 Molecular Weight 116.072 Flash Point 183.0±19.7 °C Exact Mass 116.010956 PSA 74.60000 LogP -0.01 Vapour Pressure 0.0±1.7 mmHg at 25°C Index of Refraction 1.526 InChIKey VZCYOOQTPOCHFL-UPHRSURJSA-N SMILES O=C(O)C=CC(=O)O Storage condition Store at RT. Stability Stable. Combustible. Incompatible with strong oxidizing agents, bases. Water Solubility 790 g/L (25 ºC) |
| Use of | Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes. Properties Articles122 Name maleic acid Synonym More Synonyms Maleic acid Biological Activity Description Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes. Related Catalog Natural Products >> Acids and Aldehydes Research Areas >> Infection Human Endogenous Metabolite References [1]. Fonda ML, et al. Glutamate decarboxylase. Substrate specificity and inhibition by carboxylic acids. Biochemistry. 1972 Mar 28;11(7):1304-9. [2]. Paudyal R, et al. A novel approach in acidic disinfection through inhibition of acid resistance mechanisms; Maleic acid-mediated inhibition of glutamate decarboxylase activity enhances acid sensitivity of Listeria monocytogenes. Food Microbiol. 2018 Feb;69:96-104. Chemical & Physical Properties Molecular Formula C4H4O4 Exact Mass 116.010956 PSA 74.60000 LogP -0.01 Index of Refraction 1.526 InChIKey VZCYOOQTPOCHFL-UPHRSURJSA-N SMILES O=C(O)C=CC(=O)O Storage condition Store at RT. Stability Stable. Combustible. Incompatible with strong oxidizing agents, bases. |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Chemical name |
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