CAS Number21339-55-9
SynonymsMFCD00467133; H-L-Trp(N-CH3)-OH; H-Trp(1-Me)-OH; BIDD:GT0440; (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid
Molecular FormulaC12H14N2O2
Molecular Weight218.25
Density1.28
Boiling Point429.3±35.0 °C at 760 mmHg
Melting Point223-226 ºC
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 21339-55-9 |
| Catalog No. | 2A-3184330 |
| Chinese Name | 相思子碱 |
| Synonyms | MFCD00467133; H-L-Trp(N-CH3)-OH; H-Trp(1-Me)-OH; BIDD:GT0440; (S)-2-Amino-3-(1-methyl-1H-indol-3-yl)propanoic acid |
| Molecular Formula | C12H14N2O2 |
| Molecular Weight | 218.25 |
| Density | 1.28 |
| Boiling Point | 429.3±35.0 °C at 760 mmHg |
| Melting Point | 223-226 ºC |
| Storage Condition | Refrigerated, airtight, dry place at 2-8°C |
| Application | (S)-Indoximod (1-Methyl-L-tryptophan) is an indoleamine-2,3-dioxygenase (IDO) inhibitor. (S)-Indoximod is used in cancer research. |
| HTC | 2933990090 |
| PubChem ID | 24868339 |
| MDL Number | MFCD00467133 |
| SMILES | Cn1cc(CC(N)C(=O)O)c2ccccc21 |
| InChI | InChI=1S/C12H14N2O2/c1-14-7-8(6-10(13)12(15)16)9-4-2-3-5-11(9)14/h2-5,7,10H,6,13H2,1H3,(H,15,16) |
| InChI Key | ZADWXFSZEAPBJS-JTQLQIEISA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352209 |
| Hazard Symbols | transportation |
| Bioactivity | (S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO) Target Indoleamine 2,3-Dioxygenase (IDO)[1] References [1]. Huang GL, et, al. PEG-Poly(1-Methyl-l-Tryptophan)-Based Polymeric Micelles as Enzymatically Activated Inhibitors of Indoleamine 2,3-Dioxygenase. Nanomaterials (Basel). 2019 May 9;9(5):719. [2]. Liu X, et, al. 1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells. Int J Cancer. 2018 Sep 15;143(6):1516-1529. Chemical & Physical Properties Density 1.28 Boiling Point 429.3±35.0 °C at 760 mmHg Melting Point 223-226 ºC Molecular Formula C12H14N2O2 Molecular Weight 218.252 Flash Point 213.4±25.9 °C Exact Mass 218.105530 PSA 68.25000 LogP 1.43 Vapour Pressure 0.0±1.1 mmHg at 25°C Index of Refraction 1.625 InChIKey ZADWXFSZEAPBJS-JTQLQIEISA-N SMILES Cn1cc(CC(N)C(=O)O)c2ccccc21 Storage condition 2-8°C |
| Use of | (S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer[1][2]. Properties Articles30 Name (2S)-2-amino-3-(1-methylindol-3-yl)propanoic acid Synonym More Synonyms (S)-Indoximod Biological Activity Description (S)-Indoximod (1-Methyl-L-tryptophan) is an inhibitor of indoleamine 2,3-dioxygenase (IDO). (S)-Indoximod can be used for the research of cancer[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO) Indoleamine 2,3-Dioxygenase (IDO)[1] References [1]. Huang GL, et, al. PEG-Poly(1-Methyl-l-Tryptophan)-Based Polymeric Micelles as Enzymatically Activated Inhibitors of Indoleamine 2,3-Dioxygenase. Nanomaterials (Basel). 2019 May 9;9(5):719. [2]. Liu X, et, al. 1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells. Int J Cancer. 2018 Sep 15;143(6):1516-1529. Chemical & Physical Properties Molecular Formula C12H14N2O2 Exact Mass 218.105530 PSA 68.25000 Index of Refraction 1.625 InChIKey ZADWXFSZEAPBJS-JTQLQIEISA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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