Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > 4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-Piperazinone

4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-Piperazinone

Name: 4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-Piperazinone
Brand: 2A Biotech
SKU: 2A-3183594

CAS Number675576-98-4

SynonymsNutlin-3; Nutlin-3a; Nutlin (3a); NUTLIN 3A

Molecular FormulaC30H30Cl2N4O4

Molecular Weight581.49

Density1.4±0.1 g/cm3

Appearancewhite to beige

MSDSChinese English

Cat. No.: 2A-3183594 Purity:

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Quality Control of [ 675576-98-4 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	675576-98-4
Catalog No.	2A-3183594
Chinese Name	4-[[(4S,5R)-4,5-双(4-氯苯基)-4,5-二氢-2-[4-甲氧基-2-(1-甲基乙氧基)苯基]-1H-咪唑-1-YL]羰基]-2-哌嗪酮
Synonyms	Nutlin-3; Nutlin-3a; Nutlin (3a); NUTLIN 3A
Molecular Formula	C30H30Cl2N4O4
Molecular Weight	581.49
Density	1.4±0.1 g/cm3
Appearance	white to beige
Water Solubility	DMSO: soluble5mg/mL, clear
Storage Condition	?20°C
Application	Nutlin 3a, the active isomer of Nutlin-3, is a murine double microbody 2 (MDM2) antagonist that inhibits MDM2-p53 interaction and stabilizes p53 protein, thus inducing cell cycle arrest and apoptosis.
PubChem ID	329825564
MDL Number	MFCD14636430
SMILES	COc1ccc(C2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N2C(=O)N2CCNC(=O)C2)c(OC(C)C)c1
InChI	InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37)/t27-,28+/m0/s1
InChI Key	BDUHCSBCVGXTJM-WUFINQPMSA-N
NACRES Code	NA.77
UNSPSC	12352200
Transport Info	Product name: Nutlin-3a

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4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-Piperazinone

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