
CAS Number3608-58-0
Synonyms3'-Deoxy-D-guanosine; MFCD00079149; 3'-deoxyriboguanosine; 3'-Deoxyguanosine; 3'-deoxyguanosine monohydrate; 2-amino-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-ol; 3'-deoxy-guanosine; 3'-DG
Molecular FormulaC10H13O4N5
Molecular Weight267.24
Density2.1±0.1 g/cm3
Boiling Point725.5±70.0 °C at 760 mmHg
Melting Point<300℃ (water )
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 3608-58-0 |
| Catalog No. | 2A-3183467 |
| Chinese Name | 3-脱氧鸟苷 |
| Synonyms | 3'-Deoxy-D-guanosine; MFCD00079149; 3'-deoxyriboguanosine; 3'-Deoxyguanosine; 3'-deoxyguanosine monohydrate; 2-amino-9-(3-deoxy-β-D-erythro-pentofuranosyl)-9H-purin-6-ol; 3'-deoxy-guanosine; 3'-DG |
| Molecular Formula | C10H13O4N5 |
| Molecular Weight | 267.24 |
| Density | 2.1±0.1 g/cm3 |
| Boiling Point | 725.5±70.0 °C at 760 mmHg |
| Melting Point | <300℃ (water ) |
| Storage Condition | Keep away from light, in a ventilated and dry plac |
| Application | 3'-Deoxyguanosine (guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism i |
| HTC | 2934999090 |
| PubChem ID | 585501 |
| MDL Number | MFCD28041154 |
| SMILES | NC1=NC(=O)c2ncn([C@@H]3O[C@H](CO)C[C@H]3O)c2N1 |
| InChI | InChI=1S/C10H13N5O4/c11-10-13-7-6(8(18)14-10)12-3-15(7)9-5(17)1-4(2-16)19-9/h3-5,9,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,9+/m0/s1 |
| InChI Key | InChIKey=OROIAVZITJBGSM-OBXARNEKSA-N |
| Use of | 3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Name 3'-deoxyguanosine Synonym More Synonyms 3'-Deoxyguanosine Biological Activity Description 3′-Deoxyguanosine (Guanosine, 3'-deoxy-) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C10H13N5O4 Exact Mass 267.096741 PSA 140.01000 LogP -0.72 Index of Refraction 1.907 Safety Information Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter RIDADR NONH for all modes of transport WGK Germany 3 HS Code 2934999090 Synthetic Route (2R,3R,5S)-2-(2... CAS#:3608-57-9 3'-Deoxyguanosine CAS#:3608-58-0 Literature: Bhan, Purshotam; Bhan, Anila; Hong, Mikung; Hartwell, John G.; Saunders, June M.; Hoke, GlennD Nucleosides and Nucleotides, 1997 , vol. 16, # 7-9 p. 1195 - 1199 CAS#:118-00-3 3'-Deoxyguanosine CAS#:3608-58-0 Literature: Journal of Organic Chemistry, , vol. 59, # 24 p. 7243 - 7248 N2-[(dimethylam... CAS#:1055407-32-3 3'-Deoxyguanosine CAS#:3608-58-0 Literature: Journal of Organic Chemistry, , vol. 59, # 24 p. 7243 - 7248 Precursor & DownStream Precursor 9 CAS#:3608-57-9 (2R,3R,5S)-2-(2... CAS#:118-00-3 CAS#:1055407-32-3 N2-[(dimethylam... CAS#:1053251-34-5 O-((2R,3R,4R,5R... DownStream 2 CAS#:157025-66-6 N-[9-[(2R,3R,5S... CAS#:869355-04-4 n2-(dimethylami... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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