| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1310746-10-1 |
| Catalog No. | 2A-3183098 |
| Chinese Name | NVP BGJ398 磷酸盐 |
| Synonyms | BGJ398; NVP-BGJ398 (phosphate) |
| Molecular Formula | C26H34O7N7Cl2P1 |
| Molecular Weight | 658.48 |
| Storage Condition | 2-8℃ |
| Application | Infigratinib phosphate (BGJ-398 phosphate) is an FGFR inhibitor with IC50s of 0.9, 1.4 and 1 nM for FGFR1, FGFR2 and FGFR3 respectively. It is 40 times more inhibitory than FGFR4 and VEGFR2 and has al |
| PubChem ID | 134447688 |
| MDL Number | MFCD26960938 |
| SMILES | CCN1CCN(c2ccc(Nc3cc(N(C)C(=O)Nc4c(Cl)c(OC)cc(OC)c4Cl)ncn3)cc2)CC1.O=P(O)(O)O |
| InChI | InChI=1S/C26H31Cl2N7O3.H3O4P/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)33(2)26(36)32-25-23(27)19(37-3)14-20(38-4)24(25)28;1-5(2,3)4/h6-9,14-16H,5,10-13H2,1-4H3,(H,32,36)(H,29,30,31);(H3,1,2,3,4) |
| InChI Key | GUQNHCGYHLSITB-UHFFFAOYSA-N |
| Transport Info | Product name: Infigratinib phosphate |
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