CAS Number939-19-5
Synonyms3-Hydroxycoumarine; 3-hydroxy-coumari; 3-HYDROXY-2H-CHROMEN-2-ONE; 3-hydroxy<1>benzopyran-2-one; HYDROXYCOUMARIN,3; 3-hydroxy-2-benzopyrone; 2,3-DIHYDROXYCOUMARIN; 3-hydroxychromone; EINECS 213-355-3; AURORA KA-3736; 3-Hydroxy-2H-1-benzopyran-2-on; MFCD00017490; hydroxy-coumarin
Molecular FormulaC9H6O3
Molecular Weight162.14
Density1.446 g/cm3
Boiling Point369.9ºC at 760 mmHg
Melting Point153-157 °C(lit.)
AppearanceSolid;White to Orange to Green powder to crystal
EINECS213-355-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 939-19-5 |
| Catalog No. | 2A-3182664 |
| Chinese Name | 3-羟基香豆素 |
| Synonyms | 3-Hydroxycoumarine; 3-hydroxy-coumari; 3-HYDROXY-2H-CHROMEN-2-ONE; 3-hydroxy<1>benzopyran-2-one; HYDROXYCOUMARIN,3; 3-hydroxy-2-benzopyrone; 2,3-DIHYDROXYCOUMARIN; 3-hydroxychromone; EINECS 213-355-3; AURORA KA-3736; 3-Hydroxy-2H-1-benzopyran-2-on; MFCD00017490; hydroxy-coumarin |
| Molecular Formula | C9H6O3 |
| Molecular Weight | 162.14 |
| Density | 1.446 g/cm3 |
| Boiling Point | 369.9ºC at 760 mmHg |
| Melting Point | 153-157 °C(lit.) |
| Appearance | Solid;White to Orange to Green powder to crystal |
| Storage Condition | Store at room temperature, away from light, in a v |
| Application | 3-hydroxycoumarin is a potent redox inhibitor of 15-LOX-1. 3-hydroxycoumarin was recently shown to protect sea urchin germ cells from UV-B damage. |
| EINECS | 213-355-3 |
| HTC | 2932209090 |
| PubChem ID | 24883216 |
| MDL Number | MFCD00017490 |
| SMILES | O=c1oc2ccccc2cc1O |
| InChI | InChI=1S/C9H6O3/c10-7-5-6-3-1-2-4-8(6)12-9(7)11/h1-5,10H |
| InChI Key | MJKVTPMWOKAVMS-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | transportation |
| Bioactivity | 3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Alavi SJ, Sadeghian H, Seyedi SM, Salimi A, Eshghi H. A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarin. Chem Biol Drug Des. 2018;91(6):1125‐1132. [2]. Born SL, et al. Synthesis and reactivity of coumarin 3,4-epoxide. Drug Metab Dispos. 1997;25(11):1318‐1324. [3]. Asthana S, et al. Structure-Activity Relationship Study of Hydroxycoumarins and Mushroom Tyrosinase. J Agric Food Chem. 2015;63(32):7236‐7244. Chemical & Physical Properties Density 1.446 g/cm3 Boiling Point 369.9ºC at 760 mmHg Melting Point 153-157 °C(lit.) Molecular Formula C9H6O3 Molecular Weight 162.14200 Flash Point 174.7ºC Exact Mass 162.03200 PSA 50.44000 LogP 1.49860 Index of Refraction 1.659 InChIKey MJKVTPMWOKAVMS-UHFFFAOYSA-N SMILES O=c1oc2ccccc2cc1O |
| Use of | 3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage[1][2]. Properties Name 3-hydroxycoumarin Synonym More Synonyms 3-hydroxycoumarin Biological Activity Description 3-hydroxycoumarin is a potent and redox inhibitor of human 15-LOX-1. 3-hydroxycoumarin is recently demonstrated to protect sea urchin reproductive cells against ultraviolet B damage[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Alavi SJ, Sadeghian H, Seyedi SM, Salimi A, Eshghi H. A novel class of human 15-LOX-1 inhibitors based on 3-hydroxycoumarin. Chem Biol Drug Des. 2018;91(6):1125‐1132. [2]. Born SL, et al. Synthesis and reactivity of coumarin 3,4-epoxide. Drug Metab Dispos. 1997;25(11):1318‐1324. [3]. Asthana S, et al. Structure-Activity Relationship Study of Hydroxycoumarins and Mushroom Tyrosinase. J Agric Food Chem. 2015;63(32):7236‐7244. Chemical & Physical Properties Molecular Formula C9H6O3 Exact Mass 162.03200 PSA 50.44000 LogP 1.49860 Index of Refraction 1.659 InChIKey MJKVTPMWOKAVMS-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 97.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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