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U-73343 structure, CAS 142878-12-4

U-73343

CAS Number142878-12-4

Synonyms1-(6-{[(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino}hexyl)-2,5-pyrrolidinedione; MFCD00211221; IN1024; 1-(6-{[3-methoxyestra-1,3,5(10)-trien-17-yl]amino}hexyl)pyrrolidine-2,5-dione; 1-(6-((17β-3-Methoxyestra-1,3,5(10)-triene-17-yl)amino)hexyl)-2,5-pyrrolidinedione

Molecular FormulaC29H42N2O3

Molecular Weight466.66

Purity

Density1.2±0.1 g/cm3

Boiling Point641.5±55.0 °C at 760 mmHg

Melting Point

Flash Point

Appearance

EINECS

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Cat. No.: 2A-2182265 Purity:
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Quality Control of [ 142878-12-4 ] SDS Specification MoL

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Chemical & Physical Properties
CAS Number142878-12-4
Catalog No.2A-2182265
Chinese NameU-73343
Synonyms1-(6-{[(17β)-3-Methoxyestra-1,3,5(10)-trien-17-yl]amino}hexyl)-2,5-pyrrolidinedione; MFCD00211221; IN1024; 1-(6-{[3-methoxyestra-1,3,5(10)-trien-17-yl]amino}hexyl)pyrrolidine-2,5-dione; 1-(6-((17β-3-Methoxyestra-1,3,5(10)-triene-17-yl)amino)hexyl)-2,5-pyrrolidinedione
Molecular FormulaC29H42N2O3
Molecular Weight466.66
Density1.2±0.1 g/cm3
Boiling Point641.5±55.0 °C at 760 mmHg
Storage ConditionKeep the container sealed and stored in a cool, dr
ApplicationU-73343 is an inhibitor of PLC-dependent processes, an analog of U-73122, and can be used as a negative control.
PubChem ID10236504
MDL NumberMFCD00211221
SMILESCOc1ccc2c(c1)CCC1C2CCC2(C)C(NCCCCCCN3C(=O)CCC3=O)CCC12
InChIInChI=1S/C29H42N2O3/c1-29-16-15-23-22-10-8-21(34-2)19-20(22)7-9-24(23)25(29)11-12-26(29)30-17-5-3-4-6-18-31-27(32)13-14-28(31)33/h8,10,19,23-26,30H,3-7,9,11-18H2,1-2H3/t23-,24-,25+,26+,29+/m1/s1
InChI KeyCJHWFIUASFBCKN-ZRJUGLEFSA-N
NACRES CodeNA.77
UNSPSC51111800
Hazard Symbolstransportation
BioactivityU-73343, an inhibitor of PLC (putative phospholipase C)-dependent processes, is an analog of U-73122 and can be used as a negative control[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Others References [1]. Muto Y, et al. The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell. J Pharmacol Exp Ther. 1997 Sep;282(3):1379-88. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 641.5±55.0 °C at 760 mmHg Molecular Formula C29H42N2O3 Molecular Weight 466.66 Flash Point 341.8±31.5 °C Exact Mass 466.319550 PSA 58.64000 LogP 5.49 Vapour Pressure 0.0±1.9 mmHg at 25°C Index of Refraction 1.578 InChIKey CJHWFIUASFBCKN-ZRJUGLEFSA-N SMILES COc1ccc2c(c1)CCC1C2CCC2(C)C(NCCCCCCN3C(=O)CCC3=O)CCC12 Storage condition 2-8°C
Use ofU-73343, an inhibitor of PLC (putative phospholipase C)-dependent processes, is an analog of U-73122 and can be used as a negative control[1]. Properties Articles33 Name 1-[6-[(3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl)amino]hexyl]pyrrolidine-2,5-dione Synonym More Synonyms U-73343 Biological Activity Description U-73343, an inhibitor of PLC (putative phospholipase C)-dependent processes, is an analog of U-73122 and can be used as a negative control[1]. Related Catalog Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Others References [1]. Muto Y, et al. The putative phospholipase C inhibitor U73122 and its negative control, U73343, elicit unexpected effects on the rabbit parietal cell. J Pharmacol Exp Ther. 1997 Sep;282(3):1379-88. Chemical & Physical Properties Molecular Formula C29H42N2O3 Exact Mass 466.319550 PSA 58.64000 Index of Refraction 1.578 InChIKey CJHWFIUASFBCKN-ZRJUGLEFSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available
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