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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > CHICAGO SKY BLUE 6B
CHICAGO SKY BLUE 6B structure, CAS 2610-05-1

CHICAGO SKY BLUE 6B

CAS Number2610-05-1

Synonymspaperblue6b; modrprima1; CartaBlue2G; Direct Blue 1; Direct Blue 1 Pontamine sky blue; Chicago Sky Blue; nsb6b; Chicago Sky Blue 6B; Pontamine Sky Blue 6B; EINECS 220-026-8; CHICAGO BLUE; MFCD00004020; skyblue6b; C. I. Direct blue I; inkblue6b

Molecular FormulaC34H24N6Na4O16S4

Molecular Weight992.80

Purity98%%

Density

Boiling Point

Melting Point

Flash Point

Appearancegreen blue powder

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-4182066 Purity: 98%%
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Quality Control of [ 2610-05-1 ] Purity: 98%% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number2610-05-1
Catalog No.2A-4182066
Chinese Name直接蓝1
Synonymspaperblue6b; modrprima1; CartaBlue2G; Direct Blue 1; Direct Blue 1 Pontamine sky blue; Chicago Sky Blue; nsb6b; Chicago Sky Blue 6B; Pontamine Sky Blue 6B; EINECS 220-026-8; CHICAGO BLUE; MFCD00004020; skyblue6b; C. I. Direct blue I; inkblue6b
Molecular FormulaC34H24N6Na4O16S4
Molecular Weight992.80
Purity98%
Appearancegreen blue powder
Storage ConditionSealed in a cool, dry environment.
ApplicationDirect Blue 1 (Chicago Sky Blue 6B) is a counter dye for background autofluorescence in immunofluorescent histochemistry. Structurally related to glutamate, Direct Blue 1 is a potent and competitive V
MDL NumberMFCD00004020
SMILESCOc1cc(-c2ccc(N=Nc3ccc4c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c4c3O)c(OC)c2)ccc1N=Nc1ccc2c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c2c1O.[Na+].[Na+].[Na+].[Na+]
InChIInChI=1S/C34H28N6O16S4.4Na/c1-55-23-11-15(3-7-19(23)37-39-21-9-5-17-25(57(43,44)45)13-27(59(49,50)51)31(35)29(17)33(21)41)16-4-8-20(24(12-16)56-2)38-40-22-10-6-18-26(58(46,47)48)14-28(60(52,53)54)32(36)30(18)34(22)42;;;;/h3-14,37-38H,35-36H2,1-2H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54);;;;/q;4*+1/p-4/b39-21-,40-22+;;;;
InChI KeyBPHHNXJPFPEJOF-UHFFFAOYSA-J
NACRES CodeNA.77
UNSPSC12171500
Hazard Symbolstransportation
BioactivityDirect Blue 1 (Chicago Sky Blue 6B) is a counterstain for background autofluorescence in immunofluorescence histochemistry. Direct Blue 1, structurally related to glutamate, is a potent and competitive VGLUT inhibitor without affecting plasma membrane transporters. Direct Blue 1 is the first small molecule PrP ligand capable of inhibiting Aβ binding[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Lodha N, Poojary SA. A Novel Contrast Stain for the Rapid Diagnosis of Pityriasis Versicolor: A Comparison of Chicago Sky Blue 6B Stain, Potassium Hydroxide Mount and Culture. Indian J Dermatol. 2015;60(4):340-344. [2]. Yu G, et al. The antinociceptive effects of intracerebroventricular administration of Chicago sky blue 6B, a vesicular glutamate transporter inhibitor. Behav Pharmacol. 2013;24(8):653-658. [3]. Risse E, et al. Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay. J Biol Chem. 2015;290(27):17020-17028. Chemical & Physical Properties Molecular Formula C34H24N6Na4O16S4 Molecular Weight 992.804 Exact Mass 991.972229 PSA 422.72000 LogP 10.18560 InChIKey BPHHNXJPFPEJOF-UHFFFAOYSA-J SMILES COc1cc(-c2ccc(N=Nc3ccc4c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c4c3O)c(OC)c2)ccc1N=Nc1ccc2c(S(=O)(=O)[O-])cc(S(=O)(=O)[O-])c(N)c2c1O.[Na+].[Na+].[Na+].[Na+] Storage condition Store at RT
Use ofDirect Blue 1 (Chicago Sky Blue 6B) is a counterstain for background autofluorescence in immunofluorescence histochemistry. Direct Blue 1, structurally related to glutamate, is a potent and competitive VGLUT inhibitor without affecting plasma membrane transporters. Direct Blue 1 is the first small molecule PrP ligand capable of inhibiting Aβ binding[1]. Properties Articles29 Name Chicago Sky Blue 6B,6,6'-[(3,3-Dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[4-amino-5-hydroxy-1,3-napthalenedisulphonicacid]tetrasodiumsalt Synonym More Synonyms Direct Blue 1 Biological Activity Description Direct Blue 1 (Chicago Sky Blue 6B) is a counterstain for background autofluorescence in immunofluorescence histochemistry. Direct Blue 1, structurally related to glutamate, is a potent and competitive VGLUT inhibitor without affecting plasma membrane transporters. Direct Blue 1 is the first small molecule PrP ligand capable of inhibiting Aβ binding[1]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Lodha N, Poojary SA. A Novel Contrast Stain for the Rapid Diagnosis of Pityriasis Versicolor: A Comparison of Chicago Sky Blue 6B Stain, Potassium Hydroxide Mount and Culture. Indian J Dermatol. 2015;60(4):340-344. [2]. Yu G, et al. The antinociceptive effects of intracerebroventricular administration of Chicago sky blue 6B, a vesicular glutamate transporter inhibitor. Behav Pharmacol. 2013;24(8):653-658. [3]. Risse E, et al. Identification of a Compound That Disrupts Binding of Amyloid-β to the Prion Protein Using a Novel Fluorescence-based Assay. J Biol Chem. 2015;290(27):17020-17028. Chemical & Physical Properties Molecular Formula C34H24N6Na4O16S4 Exact Mass 991.972229 PSA 422.72000 LogP 10.18560 InChIKey BPHHNXJPFPEJOF-UHFFFAOYSA-J Storage condition Store at RT
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 United Nations number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special precautions No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip.
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