Evolocumab

Name: Evolocumab
Brand: 2A Biotech
SKU: 2A-2181930

CAS Number1256937-27-5

SynonymsTarget; PCSK9[1]; References

Molecular FormulaC58H97N15O16S2Se

Molecular Weight1403.572

Boiling Point1364.0±75.0 °C at 760 mmHg

Cat. No.: 2A-2181930 Purity:

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Quality Control of [ 1256937-27-5 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	1256937-27-5
Catalog No.	2A-2181930
Chinese Name	Evolocumab
Synonyms	Target; PCSK9[1]; References
Molecular Formula	C58H97N15O16S2Se
Molecular Weight	1403.572
Boiling Point	1364.0±75.0 °C at 760 mmHg
Storage Condition	-20℃, avoid light
Application	Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab binds to the circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab can be used to study hypercholes
SMILES	CCCCN=C1NC(=Cc2ccc(-n3cnc(C)c3)c(OC)c2)C(=O)N1C(C)c1ccc(F)cc1.CCN=C1NC(=Cc2ccc(-n3cnc(C)c3)c(OC)c2)C(=O)N1C(C)c1ccc(F)cc1.COC1=NC(=Cc2ccc(-n3cnc(C)c3)c(OC)c2)C(=O)N1C(C)c1ccc(F)cc1.COc1cc(C=C2NC(=NCC3CC3)N(C(C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1.COc1cc(C=C2NC(=NCCCO)N(C(C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1
InChI Key	PUHBRGRYFZDQIV-UHFFFAOYSA-N
Transport Info	Product name: Evolocumab(anti-PCSK9)

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