CAS Number21730-93-8
Synonyms2,3-dihydroxydihydrofuran-1-one; Threonolactone; di-TMS-Threono-1,4-lactone; (3R,4S)-3,4-Dihydroxydihydrofuran-2(3H)-one; L-threonic acid-4-lactone; threonic acid-1,4-lactone; L-treono-1,4-lactone; L-Threonic acid-1,4-lactone; (3R,4S)-3,4-dihydroxyoxolan-2-one; Bis-TMS-Threono-1,4-lactone; L-Threonsaeure-4-lacton; (3R,4S)-3,4-dihydroxy-dihydrofuran-2-one
Molecular FormulaC4H6O4
Molecular Weight118.09
Purity98%%
Density0.99g/cm3
Boiling Point277.8ºC at 760mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 21730-93-8 |
| Catalog No. | 2A-4181127 |
| Chinese Name | L-threonolactone |
| Synonyms | 2,3-dihydroxydihydrofuran-1-one; Threonolactone; di-TMS-Threono-1,4-lactone; (3R,4S)-3,4-Dihydroxydihydrofuran-2(3H)-one; L-threonic acid-4-lactone; threonic acid-1,4-lactone; L-treono-1,4-lactone; L-Threonic acid-1,4-lactone; (3R,4S)-3,4-dihydroxyoxolan-2-one; Bis-TMS-Threono-1,4-lactone; L-Threonsaeure-4-lacton; (3R,4S)-3,4-dihydroxy-dihydrofuran-2-one |
| Molecular Formula | C4H6O4 |
| Molecular Weight | 118.09 |
| Purity | 98% |
| Density | 0.99g/cm3 |
| Boiling Point | 277.8ºC at 760mmHg |
| Application | L-Threonine lactone ((3R,4S)-3,4-dihydroxyoxolen-2-one) is a purine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-can |
| HTC | 2932209090 |
| PubChem ID | 3140982 |
| SMILES | O=C1OCC(O)C1O |
| InChI | InChI=1S/C4H6O4/c5-2-1-8-4(7)3(2)6/h2-3,5-6H,1H2/t2-,3+/m0/s1 |
| InChI Key | SGMJBNSHAZVGMC-STHAYSLISA-N |
| Use of | L-Threonolactone ((3R,4S)-3,4-Dihydroxyoxolan-2-one) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Name L-threonolactone Synonym More Synonyms L-threonolactone Biological Activity Description L-Threonolactone ((3R,4S)-3,4-Dihydroxyoxolan-2-one) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C4H6O4 Exact Mass 118.02700 PSA 66.76000 Index of Refraction 1.437 InChIKey SGMJBNSHAZVGMC-STHAYSLISA-N SMILES O=C1OCC(O)C1O Safety Information RIDADR NONH for all modes of transport HS Code 2932209090 Precursor & DownStream Precursor 0 DownStream 1 CAS#:74421-65-1 Butanamide,2,3,... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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