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Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile
3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile structure, CAS 1092578-46-5

3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile

CAS Number1092578-46-5

Synonyms(3R,4S)-Tofacitinib|; CS-1109; 1-Piperidinepropanenitrile,4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)--oxo-,(3R,4S); 3-((3R,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropan-enitrile; (3R,4S)-Tofacitinib

Molecular FormulaC16H20O1N6

Molecular Weight312.37

Purity

Density1.3±0.1 g/cm3

Boiling Point585.8±50.0 °C at 760 mmHg

Melting Point

Flash Point

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Cat. No.: 2A-3180278 Purity:
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Quality Control of [ 1092578-46-5 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number1092578-46-5
Catalog No.2A-3180278
Chinese Name(3R,4S)-4-甲基-3-(甲基-7H-吡咯并[2,3-d]嘧啶-4-氨基)-beta-氧代-1-哌啶丙腈
Synonyms(3R,4S)-Tofacitinib|; CS-1109; 1-Piperidinepropanenitrile,4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)--oxo-,(3R,4S); 3-((3R,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropan-enitrile; (3R,4S)-Tofacitinib
Molecular FormulaC16H20O1N6
Molecular Weight312.37
Density1.3±0.1 g/cm3
Boiling Point585.8±50.0 °C at 760 mmHg
Storage Condition-20°C
ApplicationTofacitinib (CP-690550) is a highly effective JAK3 inhibitor with an IC50 of 1 nM, which is 20 times and 100 times more potent than JAK2 and JAK1.
PubChem ID57286363
MDL NumberMFCD23160057
SMILESCC1CCN(C(=O)CC#N)CC1N(C)c1ncnc2[nH]ccc12
InChIInChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13-/m0/s1
InChI KeyUJLAWZDWDVHWOW-AAEUAGOBSA-N
Transport InfoProduct Name: (3R,4S)-Tofacitinib
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