CAS Number113231-05-3
SynonymsBIS-BOC-L-CYSTINE; MFCD00237437; BOC-L-CYSTINE extrapure; N,N-Bis(carboxymethyl)-L-lysine; N N-BOC-L-CYSTEINE; N,N'-di-Boc-cystine; N,N'-Bis-Boc-cystine; BOC-L-CYSTINE; N,N-di-Boc-L-cystine
Molecular FormulaC10H18N2O6
Molecular Weight262.26
Density1.4±0.1 g/cm3
Boiling Point537.8±50.0 °C at 760 mmHg
Melting Point>208°C
AppearanceSolid;White to Almost white powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 113231-05-3 |
| Catalog No. | 2A-3179933 |
| Chinese Name | Nα,Nα-双(羧甲基)- L -赖氨酸 水合物 |
| Synonyms | BIS-BOC-L-CYSTINE; MFCD00237437; BOC-L-CYSTINE extrapure; N,N-Bis(carboxymethyl)-L-lysine; N N-BOC-L-CYSTEINE; N,N'-di-Boc-cystine; N,N'-Bis-Boc-cystine; BOC-L-CYSTINE; N,N-di-Boc-L-cystine |
| Molecular Formula | C10H18N2O6 |
| Molecular Weight | 262.26 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 537.8±50.0 °C at 760 mmHg |
| Melting Point | >208°C |
| Appearance | Solid;White to Almost white powder to crystal |
| Storage Condition | Keep the container sealed and stored in a cool, dr |
| Application | Nα,Nα-bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4 with an IC50 of 59 nM. Nα,Nα-bis(carboxymethyl)-L-lysine can be used in related research on bitter taste recepto |
| HTC | 2922509090 |
| PubChem ID | 329826124 |
| MDL Number | MFCD00269876 |
| SMILES | NCCCCC(C(=O)O)N(CC(=O)O)CC(=O)O |
| InChI | InChI=1S/C10H18N2O6/c11-4-2-1-3-7(10(17)18)12(5-8(13)14)6-9(15)16/h7H,1-6,11H2,(H,13,14)(H,15,16)(H,17,18)/t7-/m0/s1 |
| InChI Key | SYFQYGMJENQVQT-ZETCQYMHSA-N |
| NACRES Code | NA.21 |
| UNSPSC | 12352106 |
| Use of | Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study[1][2][3]. Properties Name (S)-N-(5-AMino-1-carboxypentyl)iMinodiacetic acid hydrate Synonym More Synonyms N,N-Bis(carboxymethyl)-L-lysine Biological Activity Description Nα,Nα-Bis(carboxymethyl)-L-lysine is a competitive inhibitor of bitter taste receptor 4, with an IC50 of 59 nM. Nα,Nα-Bis(carboxymethyl)-L-lysine can be used in bitter receptors related study[1][2][3]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Pydi SP, et al. Amino acid derivatives as bitter taste receptor (T2R) blockers. J Biol Chem. 2014;289(36):25054-25066. [2]. Sidhu C, et al. Regulation of Rac1 GTPase activity by quinine through G-protein and bitter taste receptor T2R4. Mol Cell Biochem. 2017;426(1-2):129-136. [3]. Masamoto M, et al. Yoshida R. Effects of bitter receptor antagonists on behavioral lick responses of mice. Neurosci Lett. 2020;730:135041. Chemical & Physical Properties Molecular Formula C10H18N2O6 Exact Mass 262.116486 PSA 141.16000 LogP -1.77 Index of Refraction 1.552 InChIKey SYFQYGMJENQVQT-ZETCQYMHSA-N SMILES NCCCCC(C(=O)O)N(CC(=O)O)CC(=O)O Stability Moisture Sensitive Safety Information Hazard Codes Xi WGK Germany 3 HS Code 2922509090 Synthetic Route N6-Carbobenzylo... CAS#:113231-04-2 N,N-Bis(carboxy... CAS#:113231-05-3 Literature: Lin, Yu-Chung; Liang, Ming-Ren; Lin, Yu-Chen; Chen, Chao-Tsen Chemistry - A European Journal, 2011 , vol. 17, # 46 p. 13059 - 13067 N-(5-Amino-1-ca... CAS#:205379-08-4 N,N-Bis(carboxy... CAS#:113231-05-3 Literature: Journal of the American Chemical Society, , vol. 127, # 29 p. 10205 - 10215 N6-Cbz-L-Lysine CAS#:1155-64-2 N,N-Bis(carboxy... CAS#:113231-05-3 Literature: Analytical Chemistry, , vol. 78, # 17 p. 6065 - 6073 Precursor & DownStream Precursor 4 CAS#:113231-04-2 N6-Carbobenzylo... CAS#:205379-08-4 N-(5-Amino-1-ca... CAS#:1155-64-2 N6-Cbz-L-Lysine CAS#:205379-07-3 N2,N2-Bis[2-(1,... DownStream 1 CAS#:113231-04-2 N6-Carbobenzylo... |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
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