CAS Number85118-33-8
SynonymsGaboxadol hydrochloride; Isoxazolo[5,4-c]pyridin-3(2H)-one, 4,5,6,7-tetrahydro-, hydrochloride (1:1); 4,5,6,7-Tetrahydro[1,2]oxazolo[5,4-c]pyridin-3(2H)-one hydrochloride (1:1)
Molecular FormulaC6H9ClN2O2
Molecular Weight176.60
Purity98%%
Boiling Point295.7ºC at 760 mmHg
Melting Point236 °C
AppearanceSolid;White to Almost white powder to crystal
EINECS285-687-7
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 85118-33-8 |
| Catalog No. | 2A-4179795 |
| Chinese Name | GAB氧杂DOL盐酸盐 |
| Synonyms | Gaboxadol hydrochloride; Isoxazolo[5,4-c]pyridin-3(2H)-one, 4,5,6,7-tetrahydro-, hydrochloride (1:1); 4,5,6,7-Tetrahydro[1,2]oxazolo[5,4-c]pyridin-3(2H)-one hydrochloride (1:1) |
| Molecular Formula | C6H9ClN2O2 |
| Molecular Weight | 176.60 |
| Purity | 98% |
| Boiling Point | 295.7ºC at 760 mmHg |
| Melting Point | 236 °C |
| Appearance | Solid;White to Almost white powder to crystal |
| Storage Condition | room temperature, dry |
| Application | Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist of GABAA receptors containing the α4-δ subunit, producing anxiolytic and sedative effects. |
| EINECS | 285-687-7 |
| PubChem ID | 57654649 |
| MDL Number | MFCD00055180 |
| InChI | InChI=1S/C6H8N2O2.ClH/c9-6-4-1-2-7-3-5(4)10-8-6;/h7H,1-3H2,(H,8,9);1H |
| InChI Key | ZDZDSZQYRBZPNN-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Bioactivity | Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects[1]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor Target GABAA[1] References [1]. Zanettini C, et al. Comparing the discriminative stimulus effects of modulators of GABAA receptors containing α4-δ subunits with those of gaboxadol in rats. Psychopharmacology (Berl). 2016 May;233(10):2005-13. Chemical & Physical Properties Boiling Point 295.7ºC at 760 mmHg Melting Point 236 °C Molecular Formula C6H9ClN2O2 Molecular Weight 176.601 Flash Point 132.6ºC Exact Mass 176.035248 PSA 58.03000 LogP 0.74440 |
| Use of | Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects[1]. Properties Name 4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-ol Hydrochloride Synonym More Synonyms Gaboxadol hydrochloride Biological Activity Description Gaboxadol hydrochloride (Lu 02-030 hydrochloride) is a selective agonist at GABAA receptors that contain α4-δ subunits, and has anxiolytic and sedative effects[1]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> GABA Receptor References [1]. Zanettini C, et al. Comparing the discriminative stimulus effects of modulators of GABAA receptors containing α4-δ subunits with those of gaboxadol in rats. Psychopharmacology (Berl). 2016 May;233(10):2005-13. Chemical & Physical Properties Exact Mass 176.035248 PSA 58.03000 LogP 0.74440 |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified |
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