CAS Number155905-77-4
SynonymsBoc-L-Cyclobutylglycine; (S)-tert-Butoxycarbonylamino-cyclobutyl-acetic acid; (2S)-Cyclobutyl({[(2-methyl-2-propanyl)oxy]carbonyl}amino)acetic acid
Molecular FormulaC11H19O4N1
Molecular Weight229.28
Density1.2±0.1 g/cm3
Boiling Point379.1±25.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 155905-77-4 |
| Catalog No. | 2A-2179347 |
| Chinese Name | Boc-L-环丁基甘氨酸 |
| Synonyms | Boc-L-Cyclobutylglycine; (S)-tert-Butoxycarbonylamino-cyclobutyl-acetic acid; (2S)-Cyclobutyl({[(2-methyl-2-propanyl)oxy]carbonyl}amino)acetic acid |
| Molecular Formula | C11H19O4N1 |
| Molecular Weight | 229.28 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 379.1±25.0 °C at 760 mmHg |
| Storage Condition | room temperature, dry |
| Application | Boc-L-cyclobutylglycine is a glycine derivative that can be used in the synthesis of PI3K inhibitors [1]. |
| HTC | 2924299090 |
| PubChem ID | 66411209 |
| MDL Number | MFCD06659975 |
| SMILES | CC(C)(C)OC(=O)NC(C(=O)O)C1CCC1 |
| InChI | InChI=1S/C11H19NO4/c1-11(2,3)16-10(15)12-8(9(13)14)7-5-4-6-7/h7-8H,4-6H2,1-3H3,(H,12,15)(H,13,14)/t8-/m0/s1 |
| InChI Key | OHDFGIXTRBDGRB-QMMMGPOBSA-N |
| Use of | Boc-L-cyclobutylglycine is a glycine derivative that can be used for PI3K inhibitor synthesis[1]. Properties Name (S)-2-((tert-Butoxycarbonyl)amino)-2-cyclobutylacetic acid Synonym More Synonyms Boc-L-Cyclobutylglycine Biological Activity Description Boc-L-cyclobutylglycine is a glycine derivative that can be used for PI3K inhibitor synthesis[1]. Related Catalog Research Areas >> Others Signaling Pathways >> PI3K/Akt/mTOR >> PI3K References [1]. Kim YS, et al. Synthesis and biological evaluation of novel purinyl quinazolinone derivatives as PI3Kδ-specific inhibitors for the treatment of hematologic malignancies. Bioorg Med Chem. 2021 Sep 1;45:116312. Chemical & Physical Properties Molecular Formula C11H19NO4 Exact Mass 229.131409 PSA 75.63000 Index of Refraction 1.501 InChIKey OHDFGIXTRBDGRB-QMMMGPOBSA-N Safety Information Hazard Codes Xi HS Code 2924299090 Synthetic Route Total: 1 Page (2R)-2-BOC-AMIN... CAS#:116611-45-1 Boc-L-Cyclobuty... CAS#:155905-77-4 Literature: Tetrahedron Letters, , vol. 35, # 2 p. 237 - 240 CAS#:155905-73-0 Boc-L-Cyclobuty... CAS#:155905-77-4 Literature: Tetrahedron Letters, , vol. 35, # 2 p. 237 - 240 (2R)-2-BOC-AMIN... CAS#:116611-45-1 1-Bromo-3-chlor... CAS#:109-70-6 Boc-L-Cyclobuty... CAS#:155905-77-4 Literature: Tetrahedron Letters, , vol. 35, # 2 p. 237 - 240 Precursor & DownStream Precursor 2 CAS#:116611-45-1 (2R)-2-BOC-AMIN... CAS#:109-70-6 1-Bromo-3-chlor... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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