Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

Name: N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
Brand: 2A Biotech
SKU: 2A-1179280

CAS Number1207360-89-1

SynonymsGDC-0349||GDC0349; GDC-0349

Molecular FormulaC24H32O3N6

Molecular Weight452.56

Density1.3±0.1 g/cm3

Boiling Point571.3±50.0 °C at 760 mmHg

Appearancepowder

MSDSChinese English

Cat. No.: 2A-1179280 Purity:

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Quality Control of [ 1207360-89-1 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	1207360-89-1
Catalog No.	2A-1179280
Chinese Name	N-ETHYL-N'-[4-[5,6,7,8-四氢-4-[(3S)-3-甲基-4-吗啉基]-7-(3-氧杂环丁基)吡啶并[3,4-D]嘧啶-2-基]苯基]脲
Synonyms	GDC-0349\|\|GDC0349; GDC-0349
Molecular Formula	C24H32O3N6
Molecular Weight	452.56
Density	1.3±0.1 g/cm3
Boiling Point	571.3±50.0 °C at 760 mmHg
Appearance	powder
Storage Condition	-20℃
Application	GDC-0349 is a potent, ATP-competitive and selective mTOR inhibitor with a Ki of 3.8 nM. GDC-0349 inhibits mTORC1 and mTORC2 complexes.
PubChem ID	140624088
MDL Number	MFCD22417087
SMILES	CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4C)n2)CCN(C2COC2)C3)cc1
InChI	InChI=1S/C24H32N6O3/c1-3-25-24(31)26-18-6-4-17(5-7-18)22-27-21-12-29(19-14-33-15-19)9-8-20(21)23(28-22)30-10-11-32-13-16(30)2/h4-7,16,19H,3,8-15H2,1-2H3,(H2,25,26,31)/t16-/m0/s1
InChI Key	RGJOJUGRHPQXGF-INIZCTEOSA-N
Transport Info	Product name: GDC-0349

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N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea

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