CAS Number181587-01-9
SynonymsEthiprole; UNII-5527E53JNB; 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile; 5-amino-1-(2,6-dichloro-α,α,α-trifluoro-p-tolyl)-4-ethylsulfinylpyrazole-3-carbonitrile; 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-ethylsulfinylpyrazole-3-carbonitrile; 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethanesulfinyl)-1H-pyrazole-3-carbonitrile
Molecular FormulaC13H9Cl2F3N4OS
Molecular Weight397.20
Density1.69g/cm3
Boiling Point563.5ºC at 760mmHg
Melting Point~174°
Appearancewhite powder
EINECS446-630-3
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 181587-01-9 |
| Catalog No. | 2A-1179083 |
| Chinese Name | 乙虫腈 |
| Synonyms | Ethiprole; UNII-5527E53JNB; 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile; 5-amino-1-(2,6-dichloro-α,α,α-trifluoro-p-tolyl)-4-ethylsulfinylpyrazole-3-carbonitrile; 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-ethylsulfinylpyrazole-3-carbonitrile; 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethanesulfinyl)-1H-pyrazole-3-carbonitrile |
| Molecular Formula | C13H9Cl2F3N4OS |
| Molecular Weight | 397.20 |
| Density | 1.69g/cm3 |
| Boiling Point | 563.5ºC at 760mmHg |
| Melting Point | ~174° |
| Appearance | white powder |
| Storage Condition | 0-6°C |
| Application | Ethiprole is an insecticide. Produces metabolic sulfones faster than Fipronil (HY-B0822) in CYP3A4 expressing cells and in vivo mouse brain and liver. Ethiprole's sulfide, sulfoxide, sulfone and desul |
| EINECS | 446-630-3 |
| PubChem ID | 329754716 |
| MDL Number | MFCD07366662 |
| SMILES | CCS(=O)c1c(N)n(nc1C#N)-c2c(Cl)cc(cc2Cl)C(F)(F)F |
| InChI | 1S/C13H9Cl2F3N4OS/c1-2-24(23)11-9(5-19)21-22(12(11)20)10-7(14)3-6(4-8(10)15)13(16,17)18/h3-4H,2,20H2,1H3 |
| InChI Key | FNELVJVBIYMIMC-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | transportation |
| MSDS | msds/179810_2_181587_01_9.pdf |
| Bioactivity | Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Others >> Others References [1]. Caboni P, Sammelson RE, Casida JE. Phenylpyrazole insecticide photochemistry, metabolism, and GABAergic action: ethiprole compared with fipronil. J Agric Food Chem. 2003 Nov 19;51(24):7055-61. Chemical & Physical Properties Density 1.69g/cm3 Boiling Point 563.5ºC at 760mmHg Melting Point ~174° Molecular Formula C13H9Cl2F3N4OS Molecular Weight 397.20300 Flash Point 294.6ºC Exact Mass 395.98300 PSA 103.91000 LogP 5.22618 Vapour Pressure 0mmHg at 25°C Index of Refraction 1.655 InChIKey FNELVJVBIYMIMC-UHFFFAOYSA-N SMILES CCS(=O)c1c(C#N)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N Storage condition 0-6°C |
| Use of | Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity[1]. Properties Name ethiprole Synonym More Synonyms Ethiprole Biological Activity Description Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity[1]. Related Catalog Research Areas >> Infection Signaling Pathways >> Others >> Others References [1]. Caboni P, Sammelson RE, Casida JE. Phenylpyrazole insecticide photochemistry, metabolism, and GABAergic action: ethiprole compared with fipronil. J Agric Food Chem. 2003 Nov 19;51(24):7055-61. Chemical & Physical Properties Exact Mass 395.98300 PSA 103.91000 LogP 5.22618 Index of Refraction 1.655 InChIKey FNELVJVBIYMIMC-UHFFFAOYSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information European Land Transport Danger Regulations: 3077 International Maritime Transport Danger Regulations: 3077 International Air Transport Danger Regulations: 3077 14.2 United Nations shipping name European land transport hazard regulations: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Ethiprole) IMDG Code: ENVIRONMENTALLY HAZARDOUS SUBSTANCE, SOLID, N.O.S. (Ethiprole) International air transport hazard regulations: Environmentally hazardous substance, solid, n.o.s. (Ethiprole) 14.3 Transport hazard categories European land transport Dangerous Regulations: 9 International sea transport Dangerous Regulations: 9 International air transport Dangerous Regulations: 9 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: Yes International Maritime Transport Dangerous Regulations International Air Transport Dangerous Regulations: Yes Marine Pollutants (Yes/No): Yes 14.6 Special precautions further information Dangerous goods are individually packaged, with liquids exceeding 5 liters or solids exceeding 5 kilograms. The outer packaging of each independent package and the combined independent inner package must have EHS on it. Identification (according to European ADR Regulation 2.2.9.1.10, IMDG Regulation 2.10.3), |
| Related Products in Agrochemical Intermediates | ||
|---|---|---|
| 2,4-dimethyl-1-[(2-aminophenyl)thio]benzene | 2A-3178726 | 2A-3178726 |
| 4-[1-[(2,4-diamino-6-pteridinyl)methyl]-3-butynyl]benzoic acid | 146464-93-9 | 2A-3178727 |
| 6-(DIBUTYLAMINO)-1,3,5-TRIAZINE-2,4-DITHIOL | 29529-99-5 | 2A-1178784 |
| 3,4-DICHLOROACETANILIDE | 2150-93-8 | 2A-2178940 |
| 2-(2-Methoxy-4-nitrophenyl)-3-(4-nitrophenyl)-5-(2,4-disulfophenyl)-2H-tetrazolium sodium salt | 193149-74-5 | 2A-2179070 |
| 3-Bromo-2,4-Dichlorobenzoic Acid | 951884-96-1 | 2A-3179114 |
| (3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol | 135270-05-2 | 2A-4179274 |
| 5-PHENYLPENTA-2,4-DIENOIC ACID | 1552-94-9 | 2A-1179494 |
| (Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)Methyl)-2,4-diMethyl-1H-pyrrole-3-carboxaMide | 1186651-51-3 | 2A-3179611 |
| 2-(2,4-Difluorophenyl)-2-propen-1-ol | 141113-36-2 | 2A-3179744 |
| Browse all Agrochemical Intermediates products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS