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SODIUM NITROPRUSSIDE

Name: SODIUM NITROPRUSSIDE
Brand: 2A Biotech
SKU: 2A-2178618

CAS Number14402-89-2

SynonymsNitroprusside (Sodium)

Molecular FormulaNa2[Fe(CN)5NO] · 2H2O

Molecular Weight297.95

Purity≥99%

Density1.72

Appearancecrystals or chunks

EINECS238-373-9

MSDSChinese English

Symbol

Signal WordWarning

Cat. No.: 2A-2178618 Purity: ≥99%

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Quality Control of [ 14402-89-2 ] Purity: ≥99% SDS Specification MoL

Chemical & Physical Properties
CAS Number	14402-89-2
Catalog No.	2A-2178618
Chinese Name	硝普酸钠
Synonyms	Nitroprusside (Sodium)
Molecular Formula	Na2[Fe(CN)5NO] · 2H2O
Molecular Weight	297.95
Purity	≥99
Density	1.72
Appearance	crystals or chunks
Storage Condition	room temperature
Packaging	III
Application	Sodium Nitroprusside is a vasodilator that promotes the release of NO into the blood.
EINECS	238-373-9
PubChem ID	329763522
MDL Number	MFCD00149192
SMILES	O.O.[Na+].[Na+].O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N
InChI	1S/5CN.Fe.NO.2Na.2H2O/c51-2;;1-2;;;;/h;;;;;;;;;21H2/q;;;;;2-1;2+1;;
InChI Key	OIRZWVYIQXBRFC-UHFFFAOYSA-N
NACRES Code	NB.24
UNSPSC	12352300
Hazard Symbols	6.1(b)
MSDS	msds/179283_1_14402_89_2.pdf
Bioactivity	Sodium Nitroprusside is a potent vasodilator working through releasing NO spontaneously in blood.Target: OthersSodium Nitroprusside is a potent vasodilator. Sodium nitroprusside has potent vasodilating effects in arterioles and venules. Sodium Nitroprusside breaks down in circulation to release nitric oxide (NO). NO activates guanylate cyclase in vascular smooth muscle and increases intracellular production of cGMP. The end result is vascular smooth muscle relaxation, which allow vessels to dilate [1]. Sodium nitroprusside decreases the proliferation of vascular smooth muscle cells [2]. Sodium nitroprusside (5 mg/kg) significantly reduces the intestinal ischemiareperfusion injury as a nitric oxide donor in rats [3]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease References [1]. Wink, D.A., et al., The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection. Arch Biochem Biophys, 1996. 331(2): p. 241-8. [2]. Garg, U.C. and A. Hassid, Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest, 1989. 83(5): p. 1774-7. [3]. Namazi, H., Sodium nitroprusside as a nitric oxide donor in a rat intestinal ischemia reperfusion model: a novel molecular mechanism. Clinics (Sao Paulo), 2008. 63(3): p. 405. Chemical & Physical Properties Density 1.72 Molecular Formula C5FeN6Na2O Molecular Weight 261.91800 Exact Mass 261.92800 PSA 148.38000 LogP 0.29850 Appearance of Characters Liquid \| Clear tan-gold InChIKey PECOKVKJVPMJBN-UHFFFAOYSA-N SMILES [C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[Fe+4].[N-]=O.[Na+].[Na+]
Use of	Properties Name sodium nitroprusside Synonym More Synonyms sodium nitroprusside Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease References [1]. Wink, D.A., et al., The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection. Arch Biochem Biophys, 1996. 331(2): p. 241-8. [2]. Garg, U.C. and A. Hassid, Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest, 1989. 83(5): p. 1774-7. [3]. Namazi, H., Sodium nitroprusside as a nitric oxide donor in a rat intestinal ischemia reperfusion model: a novel molecular mechanism. Clinics (Sao Paulo), 2008. 63(3): p. 405. Chemical & Physical Properties Molecular Formula C5FeN6Na2O Exact Mass 261.92800 PSA 148.38000 LogP 0.29850 Appearance of Characters Liquid \| Clear tan-gold InChIKey PECOKVKJVPMJBN-UHFFFAOYSA-N SMILES [C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[Fe+4].[N-]=O.[Na+].[Na+]
Transport Info	Product name: Sodium nitroprusside

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SODIUM NITROPRUSSIDE

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