CAS Number2887-91-4
Synonyms(3Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N-methylpropan-1-amine; 3-Dibenz(b,e)oxepin-11(6H)-ylidene-N-methyl-1-propanamine; 1-Propanamine,3-dibenzb,eoxepin-11(6H)-ylidene-N-methyl-,hydrochloride; 11[6H]-[3-(METHYLAMINO)PROPYLIDENE]DIBENZ[B,E]OXEPINE HYDROCHLORIDE; nordoxepin; N-DesMethyldoxepin-d3 Hydrochloride; 11(6h)-(3-[methylamino]propylidene)dibenz[b,e]oxepine; NorDoxepinHydrochloride; (3Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N-methyl-1-propanamine; 3-Dibenzo[b,e]oxepin-11(6H)-ylidene-N-methylpropan-1-amine; demethyldoxepin; 3-(Dibenz[b,e]oxepin-11(6H)-ylidene)-N-Methyl; N-Desmethyldoxepin; N-DesMethyldoxepin Hydrochloride
Molecular FormulaC18H20ClNO
Molecular Weight301.81
Purity≥98.0 (TLC)%
Density1.1±0.1 g/cm3
Boiling Point420.8±44.0 °C at 760 mmHg
Melting Point159-160ºC
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2887-91-4 |
| Catalog No. | 2A-3178050 |
| Chinese Name | N-去甲盐酸多塞平 |
| Synonyms | (3Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N-methylpropan-1-amine; 3-Dibenz(b,e)oxepin-11(6H)-ylidene-N-methyl-1-propanamine; 1-Propanamine,3-dibenzb,eoxepin-11(6H)-ylidene-N-methyl-,hydrochloride; 11[6H]-[3-(METHYLAMINO)PROPYLIDENE]DIBENZ[B,E]OXEPINE HYDROCHLORIDE; nordoxepin; N-DesMethyldoxepin-d3 Hydrochloride; 11(6h)-(3-[methylamino]propylidene)dibenz[b,e]oxepine; NorDoxepinHydrochloride; (3Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N-methyl-1-propanamine; 3-Dibenzo[b,e]oxepin-11(6H)-ylidene-N-methylpropan-1-amine; demethyldoxepin; 3-(Dibenz[b,e]oxepin-11(6H)-ylidene)-N-Methyl; N-Desmethyldoxepin; N-DesMethyldoxepin Hydrochloride |
| Molecular Formula | C18H20ClNO |
| Molecular Weight | 301.81 |
| Purity | ≥98.0 (TLC) |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 420.8±44.0 °C at 760 mmHg |
| Melting Point | 159-160ºC |
| Appearance | powder |
| Storage Condition | -20°C Freezer |
| Application | Noldoxypine hydrochloride is the main metabolite of doxepin. Doxepin is a tricyclic antidepressant widely used to treat mild depression [1]. |
| PubChem ID | 329818430 |
| MDL Number | MFCD00135797 |
| SMILES | Cl.CNCC\C=C1/c2ccccc2COc3ccccc13 |
| InChI | 1S/C18H19NO.ClH/c1-19-12-6-10-16-15-8-3-2-7-14(15)13-20-18-11-5-4-9-17(16)18;/h2-5,7-11,19H,6,12-13H2,1H3;1H/b16-10+; |
| InChI Key | GNPPEZGJRSOKRE-QFHYWFJHSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/178667_1_2887_91_4.pdf |
| Bioactivity | Nordoxepin hydrochloride is the major metabolite of Doxepin. Doxepin is a tricyclic antidepressant that is widely prescribed for the treatment of mild depression[1]. Related Catalog Research Areas >> Neurological Disease References [1]. Negrusz A, et al. Detection of doxepin and its major metabolite desmethyldoxepin in hair following drug therapy. J Anal Toxicol. 1998;22(6):531-536. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 420.8±44.0 °C at 760 mmHg Melting Point 159-160ºC Molecular Formula C18H20ClNO Molecular Weight 265.350 Flash Point 174.5±17.9 °C Exact Mass 265.146667 PSA 21.26000 LogP 4.59 Appearance of Characters powder | white to off-white Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.635 InChIKey GNPPEZGJRSOKRE-UHFFFAOYSA-N SMILES CNCCC=C1c2ccccc2COc2ccccc21.Cl Storage condition -20°C Freezer |
| Use of | Nordoxepin hydrochloride is the major metabolite of Doxepin. Doxepin is a tricyclic antidepressant that is widely prescribed for the treatment of mild depression[1]. Properties Articles26 Name Nordoxepin Hydrochloride Synonym More Synonyms nordoxepin Biological Activity Description Nordoxepin hydrochloride is the major metabolite of Doxepin. Doxepin is a tricyclic antidepressant that is widely prescribed for the treatment of mild depression[1]. Related Catalog Research Areas >> Neurological Disease References [1]. Negrusz A, et al. Detection of doxepin and its major metabolite desmethyldoxepin in hair following drug therapy. J Anal Toxicol. 1998;22(6):531-536. Chemical & Physical Properties Exact Mass 265.146667 PSA 21.26000 Appearance of Characters powder | white to off-white Index of Refraction 1.635 InChIKey GNPPEZGJRSOKRE-UHFFFAOYSA-N |
| Transport Info | Product name: Nordoxepin hydrochloride |
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