CAS Number72599-27-0
SynonymsButyldeoxynojirimycin; N-Butyldeoxynojirimycin; N-Butyl-deoxynojirimycin; 1,5-(BUTYLIMINO)-1,5-DIDEOXY-D-GLUCITOL; N-Butylmoranoline; (2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol; (2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol; MFCD00272581; N-(n-Butyl)deoxynojirimycin; BuDNJ; NB-DNJ; miglustat; N-butyl-1-deoxynojirimycin; n-Butyl deoxynojirimycin; Zavesca; n-Butyl dnj
Molecular FormulaC10H21NO4
Molecular Weight219.28
Purity≥98 (TLC)%
Density1.2±0.1 g/cm3
Boiling Point394.7±42.0 °C at 760 mmHg
Appearancefilm (dried in situ)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 72599-27-0 |
| Catalog No. | 2A-3178009 |
| Chinese Name | 麦格司他 |
| Synonyms | Butyldeoxynojirimycin; N-Butyldeoxynojirimycin; N-Butyl-deoxynojirimycin; 1,5-(BUTYLIMINO)-1,5-DIDEOXY-D-GLUCITOL; N-Butylmoranoline; (2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol; (2R,3R,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol; MFCD00272581; N-(n-Butyl)deoxynojirimycin; BuDNJ; NB-DNJ; miglustat; N-butyl-1-deoxynojirimycin; n-Butyl deoxynojirimycin; Zavesca; n-Butyl dnj |
| Molecular Formula | C10H21NO4 |
| Molecular Weight | 219.28 |
| Purity | ≥98 (TLC) |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 394.7±42.0 °C at 760 mmHg |
| Appearance | film (dried in situ) |
| Storage Condition | Store in an airtight container in a cool, dry plac |
| Application | Miglustat (OGT918) is a glucosylceramide synthase inhibitor that can act on type I Gaucher disease. |
| HTC | 2933399090 |
| PubChem ID | 24892070 |
| MDL Number | MFCD00272581 |
| SMILES | CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |
| InChI | 1S/C10H21NO4/c1-2-3-4-11-5-8(13)10(15)9(14)7(11)6-12/h7-10,12-15H,2-6H2,1H3/t7-,8+,9-,10-/m1/s1 |
| InChI Key | UQRORFVVSGFNRO-UTINFBMNSA-N |
| NACRES Code | NA.32 |
| UNSPSC | 12352200 |
| MSDS | msds/178618_1_72599_27_0.pdf |
| Use of | Properties Articles18 Name miglustat Synonym More Synonyms miglustat Biological Activity Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Abian, O., et al., Therapeutic strategies for Gaucher disease: miglustat (NB-DNJ) as a pharmacological chaperone for glucocerebrosidase and the different thermostability of velaglucerase alfa and imiglucerase. Mol Pharm, 2011. 8(6): p. 2390-7. [2]. van Giersbergen, P.L. and J. Dingemanse, Influence of food intake on the pharmacokinetics of miglustat, an inhibitor of glucosylceramide synthase. J Clin Pharmacol, 2007. 47(10): p. 1277-82. Chemical & Physical Properties Molecular Formula C10H21NO4 Exact Mass 219.147064 PSA 84.16000 Index of Refraction 1.546 InChIKey UQRORFVVSGFNRO-UTINFBMNSA-N Storage condition 2-8℃ Safety Information Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter RIDADR NONH for all modes of transport HS Code 2933399090 Synthetic Route 1-Deoxynojirimy... 19130-96-2 Butyraldehyde 72599-27-0 Literature: Concia, Alda Lisa; Lozano, Caries; Castillo, Jose A.; Parella, Teodor; Joglar, Jesus; Clapes, Pere Chemistry - A European Journal, 2009 , vol. 15, # 15 p. 3808 - 3816 N-butyl 2,3,4,6... 227932-82-3 72599-27-0 Literature: Matos, Carlos R. R.; Lopes, Rosangela S. C.; Lopes, Claudio C. Synthesis, 1999 , # 4 p. 571 - 573 1-Bromobutane 1-Deoxynojirimy... 19130-96-2 72599-27-0 Literature: Journal of Medicinal Chemistry, , vol. 38, # 13 p. 2349 - 2356 Precursor & DownStream Precursor 8 CAS#:19130-96-2 1-Deoxynojirimycin CAS#:123-72-8 Butyraldehyde CAS#:109-65-9 1-Bromobutane CAS#:1538-75-6 TRIMETHYLACETIC... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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