CAS Number12771-72-1
SynonymsVerruculogen; VERRUCULOGEN FROM PENICILLIUM VERRUCULOS; VERRUCOLOGEN; tr1; Verruculogenresearch grade; 3h)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimeth; TR-1TOXIN
Molecular FormulaC20H24BrN3O4
Molecular Weight511.567
Density1.5±0.1 g/cm3
Boiling Point738.4±60.0 °C at 760 mmHg
Melting Point233ºC
Appearancewhite powder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 12771-72-1 |
| Catalog No. | 2A-1177740 |
| Chinese Name | 震颤真菌毒素 |
| Synonyms | Verruculogen; VERRUCULOGEN FROM PENICILLIUM VERRUCULOS; VERRUCOLOGEN; tr1; Verruculogenresearch grade; 3h)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimeth; TR-1TOXIN |
| Molecular Formula | C20H24BrN3O4 |
| Molecular Weight | 511.567 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 738.4±60.0 °C at 760 mmHg |
| Melting Point | 233ºC |
| Appearance | white powder |
| Storage Condition | 2-8°C |
| Application | Verruculogen is a toxin produced primarily by Penicillium and Aspergillus species that causes severe tremors in infected animals. Verruculogen inhibits Ca2+-activated K+ channels. Verruculogen is an M |
| HTC | 38220090 |
| SMILES | COc1ccc2c3c4n(c2c1)C(C=C(C)C)OOC(C)(C)CC4N1C(=O)C2CCCN2C(=O)C1(O)C3O |
| InChI | InChI=1S/C27H33N3O7/c1-14(2)11-20-29-18-12-15(35-5)8-9-16(18)21-22(29)19(13-26(3,4)37-36-20)30-24(32)17-7-6-10-28(17)25(33)27(30,34)23(21)31/h8-9,11-12,17,19-20,23,31,34H,6-7,10,13H2,1-5H3 |
| InChI Key | LRXYHMMJJCTUMY-GWXUGYLUSA-N |
| Bioactivity | Verruculogen is a toxin produced mainly by Penicillium and Aspergillus spp. and causes severe tremors in affected animals. Verruculogen inhibits Ca2+-activated K+ channels. Verruculogen is an M phase inhibitor of the mammalian cell cycle[1][2][3]. Related Catalog Research Areas >> Infection Signaling Pathways >> Others >> Others References [1]. Luciane M. Kawashima, et al. The development of an analytical method for two mycotoxins, patulin and verruculogen, and survey of their presence in commercial tomato pulp. Brazilian Journal of Microbiology [2]. Knaus HG, et al. Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels. Biochemistry. 1994 May 17;33(19):5819-28. [3]. Cui CB, et al. Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. II. Physico-chemical properties and structures. J Antibiot (Tokyo). 1996 Jun;49(6):534-40. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 738.4±60.0 °C at 760 mmHg Melting Point 233ºC Molecular Formula C20H24BrN3O4 Molecular Weight 511.567 Flash Point 400.3±32.9 °C Exact Mass 511.231842 PSA 112.01000 LogP 2.60 Vapour Pressure 0.0±2.6 mmHg at 25°C Index of Refraction 1.691 InChIKey LRXYHMMJJCTUMY-GWXUGYLUSA-N SMILES COc1ccc2c3c4n(c2c1)C(C=C(C)C)OOC(C)(C)CC4N1C(=O)C2CCCN2C(=O)C1(O)C3O Storage condition 2-8°C |
| Use of | Verruculogen is a toxin produced mainly by Penicillium and Aspergillus spp. and causes severe tremors in affected animals. Verruculogen inhibits Ca2+-activated K+ channels. Verruculogen is an M phase inhibitor of the mammalian cell cycle[1][2][3]. Properties Articles35 Name verruculogen Synonym More Synonyms Verruculogen Biological Activity Description Verruculogen is a toxin produced mainly by Penicillium and Aspergillus spp. and causes severe tremors in affected animals. Verruculogen inhibits Ca2+-activated K+ channels. Verruculogen is an M phase inhibitor of the mammalian cell cycle[1][2][3]. Related Catalog Research Areas >> Infection Signaling Pathways >> Others >> Others References [1]. Luciane M. Kawashima, et al. The development of an analytical method for two mycotoxins, patulin and verruculogen, and survey of their presence in commercial tomato pulp. Brazilian Journal of Microbiology [2]. Knaus HG, et al. Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels. Biochemistry. 1994 May 17;33(19):5819-28. Chemical & Physical Properties Molecular Formula C20H24BrN3O4 Exact Mass 511.231842 PSA 112.01000 Index of Refraction 1.691 InChIKey LRXYHMMJJCTUMY-GWXUGYLUSA-N |
| Transport Info | Product name: Penicillin verrucospora |
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