| Chemical & Physical Properties | |
|---|---|
| CAS Number | 32695-27-5 |
| Catalog No. | 2A-3177434 |
| Chinese Name | 羟胺氨苯砜 |
| Synonyms | N-[4-(4-aminophenyl)sulfonylphenyl]hydroxylamine |
| Molecular Formula | C12H12N2O3S |
| Molecular Weight | 264.30000 |
| Density | 1.464g/cm3 |
| Boiling Point | 531.1ºC at 760mmHg |
| Melting Point | 194ºC dec. |
| Storage Condition | Amber Vial, -20°C Freezer |
| Application | Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and the production of reactive oxygen species. Dapsone hydroxylamine has anti-inflamma |
| HTC | 2922199090 |
| SMILES | Nc1ccc(S(=O)(=O)c2ccc(NO)cc2)cc1 |
| InChI | InChI=1S/C12H12N2O3S/c13-9-1-5-11(6-2-9)18(16,17)12-7-3-10(14-15)4-8-12/h1-8,14-15H,13H2 |
| InChI Key | IYDSJDWESCGRKW-UHFFFAOYSA-N |
| Use of | Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity[1]. Properties Name Dapsone Hydroxylamine Synonym More Synonyms Dapsone hydroxylamine Biological Activity Description Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity[1]. Related Catalog Research Areas >> Inflammation/Immunology References [1]. Albuquerque RV, et al. In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells. PLoS One. 2015 Aug 18;10(8):e0134768. [2]. Wozel G, et al. Dapsone hydroxylamine inhibits the LTB4-induced chemotaxis of polymorphonuclear leukocytes into human skin: results of a pilot study. Inflamm Res. 1997 Oct;46(10):420-2. Chemical & Physical Properties Molecular Formula C12H12N2O3S Exact Mass 264.05700 PSA 100.80000 LogP 3.63770 Index of Refraction 1.69 InChIKey IYDSJDWESCGRKW-UHFFFAOYSA-N Stability Light Sensitive, Temperature Sensitive Safety Information HS Code 2922199090 Synthetic Route Total: 1 Page Benzenamine,4-[... CAS#:1948-92-1 Dapsone hydroxy... CAS#:32695-27-5 Literature: Vyas, Piyush M.; Roychowdhury, Sanjoy; Woster, Patrick M.; Svensson, Craig K. Biochemical Pharmacology, 2005 , vol. 70, # 2 p. 275 - 286 4,4'-Diaminodip... CAS#:80-08-0 Dapsone hydroxy... CAS#:32695-27-5 Literature: Clinical Pharmacology and Therapeutics, , vol. 58, # 5 p. 556 - 566 Precursor & DownStream Precursor 2 CAS#:1948-92-1 Benzenamine,4-[... CAS#:80-08-0 4,4'-Diaminodip... DownStream 1 CAS#:80-08-0 4,4'-Diaminodip... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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