CAS Number1621-56-3
Synonyms7-methoxy-3-phenylchromone; 7-Methoxy-3-phenyl-chromen-4-on; 7-methoxy-3-phenyl-4H-1-benzopyran-4-one; 7-methoxy-3-phenyl-4H-chromen-4-one; 7-Methoxy Isoflavone; 7-methoxy-3-phenyl-chromen-4-one; 7-Methoxyisoflavone
Molecular FormulaC16H12O3
Molecular Weight252.27
Density1.24g/cm3
Boiling Point421.2ºC at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1621-56-3 |
| Catalog No. | 2A-2176261 |
| Chinese Name | 7-甲氧基异黄酮 |
| Synonyms | 7-methoxy-3-phenylchromone; 7-Methoxy-3-phenyl-chromen-4-on; 7-methoxy-3-phenyl-4H-1-benzopyran-4-one; 7-methoxy-3-phenyl-4H-chromen-4-one; 7-Methoxy Isoflavone; 7-methoxy-3-phenyl-chromen-4-one; 7-Methoxyisoflavone |
| Molecular Formula | C16H12O3 |
| Molecular Weight | 252.27 |
| Density | 1.24g/cm3 |
| Boiling Point | 421.2ºC at 760 mmHg |
| Storage Condition | 2-8℃ |
| Application | 7-Methoxyisoflavone is an isoflavone derivative and an activator of adenosine monophosphate-activated protein kinase (AMPK). |
| HTC | 2932999099 |
| MDL Number | MFCD00181416 |
| SMILES | COc1ccc2c(=O)c(-c3ccccc3)coc2c1 |
| InChI | InChI=1S/C16H12O3/c1-18-12-7-8-13-15(9-12)19-10-14(16(13)17)11-5-3-2-4-6-11/h2-10H,1H3 |
| InChI Key | IECSQLKWZBEUGA-UHFFFAOYSA-N |
| MSDS | msds/176771_1_1621_56_3.pdf |
| Use of | 7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK). Properties Name 7-methoxy-3-phenylchromen-4-one Synonym More Synonyms 7-Methoxyisoflavone Biological Activity Description 7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK). Related Catalog Signaling Pathways >> Epigenetics >> AMPK Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Research Areas >> Cancer Natural Products >> Flavonoids Research Areas >> Metabolic Disease In Vitro 7-Methoxyisoflavone is an isoflavone derivative and also an activator of adenosine monophosphate-activated protein kinase (AMPK). When serum-starved cells are treated with 10 % FBS in the presence of 7-methoxyisoflavone, the serum-induced decrease in AMPK phosphorylation is prevented[1]. References [1]. Hyeryoung Jung, et al. Isoflavones as modulators of adenosine monophosphate-activated protein kinase. Applied Biological Chemistry. 2016. 59, 217-225. Chemical & Physical Properties Molecular Formula C16H12O3 Exact Mass 252.07900 PSA 39.44000 LogP 3.46860 Index of Refraction 1.614 InChIKey IECSQLKWZBEUGA-UHFFFAOYSA-N Storage condition 2-8℃ Safety Information HS Code 2932999099 Synthetic Route 2-Hydroxy-4-met... 2-Bromoacetophe... 7-Methoxyisofla... Literature: Mishra, Priya; Singh, Sarita; Ankit, Preyas; Fatma, Shahin; Singh, Divya; Singh, Jagdamba Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 4 p. 1070 - 1076 7-Hydroxyisofla... 13057-72-2 methyl iodide 7-Methoxyisofla... Literature: Gao, Guang-Yao; Li, Dian-Jun; Keung, Wing Ming Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 18 p. 4069 - 4081 1-(2-HYDROXY-2-... 18439-96-8 N,N-Dimethylfor... 7-Methoxyisofla... Literature: Balasubramanian, Sreenivasan; Nair, Muraleedharan G. Synthetic Communications, 2000 , vol. 30, # 3 p. 469 - 484 Precursor & DownStream Precursor 9 CAS#:673-22-3 2-Hydroxy-4-met... CAS#:70-11-1 2-Bromoacetophenone CAS#:13057-72-2 7-Hydroxyisoflavone CAS#:74-88-4 methyl iodide DownStream 2 CAS#:13057-72-2 7-Hydroxyisoflavone CAS#:75989-82-1 6-chloro-7-meth... |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |
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