| Chemical & Physical Properties | |
|---|---|
| CAS Number | 43153-07-7 |
| Catalog No. | 2A-3175279 |
| Chinese Name | rac 2-(4-甲酰基苯基)丙酸(布洛芬杂质K) |
| Synonyms | 2-(4-formylphenyl)propanoic acid |
| Molecular Formula | C10H10O3 |
| Molecular Weight | 178.18 |
| Storage Condition | 2-8°C |
| Application | Ibuprofen Impurity K is the impurity of Ibuprofen. Ibuprofen is an inhibitor of COX-1 and COX-2, with IC50 values of 13 μM and 370 μM respectively, and has anti-inflammatory activity. |
| HTC | 2918300090 |
| MDL Number | MFCD08275588 |
| SMILES | OC(C(C)C1=CC=C(C([H])=O)C=C1)=O |
| InChI | 1S/C10H10O3/c1-7(10(12)13)9-4-2-8(6-11)3-5-9/h2-7H,1H3,(H,12,13) |
| InChI Key | IAXYHYOWEQQFMC-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/175703_1_43153_07_7.pdf |
| Use of | Ibuprofen Impurity K is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1]. Properties Name rac 2-(4-Formylphenyl)propionic Acid Synonym More Synonyms Ibuprofen Impurity K Biological Activity Description Ibuprofen Impurity K is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1]. Related Catalog Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX References [1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. Chemical & Physical Properties Molecular Formula C10H10O3 Exact Mass 178.06300 PSA 54.37000 LogP 1.68720 InChIKey IAXYHYOWEQQFMC-UHFFFAOYSA-N Safety Information HS Code 2918300090 Synthetic Route rac 2-(4-Formyl... CAS#:43153-04-4 Ibuprofen Impurity K CAS#:43153-07-7 Literature: Maillard; Langlois; Delaunay; Tri 1973 , vol. 8, # 4 p. 487 - 494 Benzeneacetic a... CAS#:43153-03-3 Ibuprofen Impurity K CAS#:43153-07-7 Literature: Maillard; Langlois; Delaunay; Tri 1973 , vol. 8, # 4 p. 487 - 494 ETHYL 2-PHENYLP... CAS#:2510-99-8 Ibuprofen Impurity K CAS#:43153-07-7 Literature: Maillard; Langlois; Delaunay; Tri 1973 , vol. 8, # 4 p. 487 - 494 Precursor & DownStream Precursor 4 CAS#:43153-04-4 rac 2-(4-Formyl... CAS#:43153-03-3 Benzeneacetic a... CAS#:2510-99-8 ETHYL 2-PHENYLP... CAS#:15687-27-1 DownStream 1 CAS#:34961-64-3 3-(4-Formylphen... |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives. Supervision conditions:None. VAT: 17.0%. Tax rebate rate:9.0%. MFN tariff: 6.5%. General tariff:30.0% |
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