CAS Number150824-47-8
SynonymsMFCD01631161; Capstar; (E)-N-[(6-Chloropyridin-3-yl)methyl]-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine; (E)-N-(6-chloro-3-pyridylmethyl)-N-ethyl-N'-methyl-2-nitrovinylidenediamine; (E)-N-(6-Chloro-3-pyridylmethyl)-N-ethyl-N'-methyl-2-nitrovinylidenediamine; (E)-N-[(6-Chlorpyridin-3-yl)methyl]-N-ethyl-N'-methyl-2-nitroethen-1,1-diamin; (1E)-N-[(6-chloro-3-pyridinyl)methyl]-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamine; Nitenpyram; (1E)-N-[(6-chloropyridin-3-yl)methyl]-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine; (E)-N-[(6-Chloro-3-pyridinyl)methyl]-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamine; (E)-N-((6-Chloropyridin-3-yl)methyl)-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine; (E)-1-N'-[(6-chloropyridin-3-yl)methyl]-1-N'-ethyl-1-N-methyl-2-nitroethene-1,1-diamine
Molecular FormulaC11H15ClN4O2
Molecular Weight270.72
Density1.3±0.1 g/cm3
Boiling Point417.2±45.0 °C at 760 mmHg
Melting Point72ºC
Appearancelight yellow crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 150824-47-8 |
| Catalog No. | 2A-2175185 |
| Chinese Name | 烯啶虫胺 |
| Synonyms | MFCD01631161; Capstar; (E)-N-[(6-Chloropyridin-3-yl)methyl]-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine; (E)-N-(6-chloro-3-pyridylmethyl)-N-ethyl-N'-methyl-2-nitrovinylidenediamine; (E)-N-(6-Chloro-3-pyridylmethyl)-N-ethyl-N'-methyl-2-nitrovinylidenediamine; (E)-N-[(6-Chlorpyridin-3-yl)methyl]-N-ethyl-N'-methyl-2-nitroethen-1,1-diamin; (1E)-N-[(6-chloro-3-pyridinyl)methyl]-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamine; Nitenpyram; (1E)-N-[(6-chloropyridin-3-yl)methyl]-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine; (E)-N-[(6-Chloro-3-pyridinyl)methyl]-N-ethyl-N'-methyl-2-nitro-1,1-ethenediamine; (E)-N-((6-Chloropyridin-3-yl)methyl)-N-ethyl-N'-methyl-2-nitroethene-1,1-diamine; (E)-1-N'-[(6-chloropyridin-3-yl)methyl]-1-N'-ethyl-1-N-methyl-2-nitroethene-1,1-diamine |
| Molecular Formula | C11H15ClN4O2 |
| Molecular Weight | 270.72 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 417.2±45.0 °C at 760 mmHg |
| Melting Point | 72ºC |
| Appearance | light yellow crystal |
| Storage Condition | 0-6°C |
| Application | Nitenpyram is a neonicotinoid and insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral, fast-acting insecticide used to control sucking insects in cats, |
| HTC | 2933399027 |
| PubChem ID | 329756597 |
| MDL Number | MFCD01631161 |
| SMILES | CCN(Cc1ccc(Cl)nc1)\C(NC)=C\[N+]([O-])=O |
| InChI | 1S/C11H15ClN4O2/c1-3-15(11(13-2)8-16(17)18)7-9-4-5-10(12)14-6-9/h4-6,8,13H,3,7H2,1-2H3/b11-8+ |
| InChI Key | CFRPSFYHXJZSBI-DHZHZOJOSA-N |
| Beilstein/REAXYS | 8489488 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | transportation |
| MSDS | msds/175603_1_150824_47_8.pdf |
| Bioactivity | Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals[1][2]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR In Vivo Nitenpyram is administered orally (1 mg/kg) for the short-term control of fleas in dogs and cats. Fleas start to fall from the animals 30 minutes post-administration and one dose can protect animals for 1-2 days[1]. Since Nitenpyram is highly lipophilic, it is administered orally after the meal in order to induce bile flow to help dissolve the chemical, thereby increasing GI absorption of the drug. It is rapidly and completely absorbed from the GI tract in less than 90 minutes and is completely excreted in urine within 48 hours after oral administration to dogs and cats. Nitenpyram undergoes hydroxylation, followed by conjugation in the liver. The conjugates of Nitenpyram are excreted in the urine and Nitenpyram is not accumulated in body tissues. The plasma half-life of Nitenpyram in dogs and cats are 3 and 8 hours, respectively. It is likely that animals with liver and/or kidney problems may have longer plasma half-life of Nitenpyram[1]. References [1]. Vo DT, et al. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals. J Vet Pharmacol Ther. 2010 Aug;33(4):315-22. [2]. Rust MK, et al. Efficacy and longevity of nitenpyram against adult cat fleas (Siphonaptera: Pulicidae). J Med Entomol. 2003 Sep;40(5):678-81. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 417.2±45.0 °C at 760 mmHg Melting Point 72ºC Molecular Formula C11H15ClN4O2 Molecular Weight 270.715 Flash Point 206.1±28.7 °C Exact Mass 270.088348 PSA 73.98000 LogP 1.90 Vapour Pressure 0.0±1.0 mmHg at 25°C Index of Refraction 1.568 InChIKey CFRPSFYHXJZSBI-DHZHZOJOSA-N SMILES CCN(Cc1ccc(Cl)nc1)C(=C[N+](=O)[O-])NC Storage condition 0-6°C |
| Use of | Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals[1][2]. Properties Name (E)-nitenpyram Synonym More Synonyms Nitenpyram Biological Activity Description Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals[1][2]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> nAChR Signaling Pathways >> Neuronal Signaling >> nAChR References [1]. Vo DT, et al. Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animals. J Vet Pharmacol Ther. 2010 Aug;33(4):315-22. [2]. Rust MK, et al. Efficacy and longevity of nitenpyram against adult cat fleas (Siphonaptera: Pulicidae). J Med Entomol. 2003 Sep;40(5):678-81. Chemical & Physical Properties Exact Mass 270.088348 PSA 73.98000 Index of Refraction 1.568 InChIKey CFRPSFYHXJZSBI-DHZHZOJOSA-N |
| Tax Rebate | 9.0% |
| Supervision | S. Import and export pesticide registration certificate |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
| Related Products in Agrochemical Intermediates | ||
|---|---|---|
| 2,4-DIAMINO-6,7-DIISOPROPYLPTERIDINE PHOSPHATE SALT | 84176-65-8 | 2A-2174841 |
| (2,4-dihydroxy-5-isopropylphenyl)(5-((4-Methylpiperazin-1-yl)Methyl)isoindolin-2-yl)Methanone | 912999-49-6 | 2A-1174996 |
| BETA-CYPERMETHRIN | 86752-99-0 | 2A-2175082 |
| Indoxacarb | 144171-61-9 | 2A-2175094 |
| Flucarbazone sodium | 181274-17-9 | 2A-2175182 |
| 3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro | 878671-96-6 | 2A-2175213 |
| Cypermethrin, High Effect | 86753-92-6 | 2A-1175295 |
| 2,4-DIAMINO-6-DIMETHYLAMINO-1,3,5-TRIAZINE | 1985-46-2 | 2A-3175409 |
| 2-(DiethylaMino)-N-(2,4-diMethylphenyl)acetaMide Hydrochloride | 17289-54-2 | 2A-3175444 |
| 3-BroMo-2,4-difluoropyridine | 1227502-60-4 | 2A-1175572 |
| Browse all Agrochemical Intermediates products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS