EN
0
Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > Nafarelin Acetate
Nafarelin Acetate structure, CAS 86220-42-0

Nafarelin Acetate

CAS Number86220-42-0

Synonymsnafarelin acetate hydrate; nafarelin acetate; MFCD00895733

Molecular FormulaC68H89N17O16

Molecular Weight1322.47 (anhydrous free base basis)

Purity≥95 (HPLC)%

Density

Boiling Point1840.1ºC at 760 mmHg

Melting Point

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-3175146 Purity: ≥95 (HPLC)%
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 86220-42-0 ] Purity: ≥95 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number86220-42-0
Catalog No.2A-3175146
Chinese Name醋酸萘法瑞林
Synonymsnafarelin acetate hydrate; nafarelin acetate; MFCD00895733
Molecular FormulaC68H89N17O16
Molecular Weight1322.47 (anhydrous free base basis)
Purity≥95 (HPLC)
Boiling Point1840.1ºC at 760 mmHg
Appearancesolid
Storage Condition2-8°C, sealed, dry
PubChem ID329818673
MDL NumberMFCD00895733
SMILESO.CC(O)=O.CC(C)C[C@H](NC(=O)[C@@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@H](CO)NC(=O)[C@H](Cc4c[nH]c5ccccc45)NC(=O)[C@H](Cc6cnc[nH]6)NC(=O)[C@@H]7CCC(=O)N7)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N8CCC[C@H]8C(=O)NCC(N)=O
InChI1S/C66H83N17O13.C2H4O2.H2O/c1-36(2)25-48(58(89)76-47(13-7-23-71-66(68)69)65(96)83-24-8-14-54(83)64(95)73-33-55(67)86)77-60(91)50(28-38-15-18-39-9-3-4-10-40(39)26-38)78-59(90)49(27-37-16-19-43(85)20-17-37)79-63(94)53(34-84)82-61(92)51(29-41-31-72-45-12-6-5-11-44(41)45)80-62(93)52(30-42-32-70-35-74-42)81-57(88)46-21-22-56(87)75-46;1-2(3)4;/h3-6,9-12,15-20,26,31-32,35-36,46-54,72,84-85H,7-8,13-14,21-25,27-30,33-34H2,1-2H3,(H2,67,86)(H,70,74)(H,73,95)(H,75,87)(H,76,89)(H,77,91)(H,78,90)(H,79,94)(H,80,93)(H,81,88)(H,82,92)(H4,68,69,71);1H3,(H,3,4);1H2/t46-,47-,48-,49-,50+,51-,52-,53-,54-;;/m0../s1
InChI KeyFSBTYDWUUWLHBD-UDXTWCDOSA-N
NACRES CodeNA.77
UNSPSC12352200
Hazard Symbolstransportation
MSDSmsds/175561_1_86220_42_0.pdf
Use ofNafarelin is a gonadotropin-releasing hormone agonist (GnRH agonist) which acts as an analog of GnRH. Nafarelin increases the release of FSH and LH by the anterior pituitary, which in turn leads to an increase of estrogen/progesterone. When administered, Nafarelin has the purpose of causing increase estrogen that will negatively feed back upon hypothalamus to decrease GnRH ( negative feedback loop ) Through negative feedback, Nafarelin causes a decrease in pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Nafarelin may be used in the treatment of estrogen-dependent conditions (such as endometriosis or uterine fibroids), to treat central precocious puberty, and to control ovarian stimulation in IVF. It is normally delivered via a nasal spray. Nafarelin acetate is marketed by Searle (now part of Pfizer) under the brand name Synarel. Properties Articles27 Name 5-oxo-l-prolyl-l-histidyl-l-tryptophyl-l-seryl-l-tyrosyl-3-(2-naphthyl)-d-alanyl-l-leucyl-l-arginyl-l-prolylglycinamide acetate hydrate Synonym More Synonyms Chemical & Physical Properties Molecular Formula C68H89N17O16 Exact Mass 1399.67000 PSA 518.66000 LogP 3.89850 InChIKey FSBTYDWUUWLHBD-UDXTWCDOSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available The company is not responsible for any damage caused by any operation or contact with the above products. For more terms of use, see invoice or package The reverse side of the mounting strip.
Related Products in Specialty Chemicals
Myristoyl Hexapeptide-4959610-44-72A-3175139
Myristoyl Hexapeptide-232A-31751402A-3175140
KGF148348-15-62A-3175141
Promote the stem cell growth factor2A-31751422A-3175142
Romurtide78113-36-72A-3175145
Histrelin Acetate220810-26-42A-3175147
Thymodepressin OR Orilotimod186087-26-32A-3175148
Pentetreotide138661-02-62A-3175149
Carperitide89213-87-62A-3175150
Glatiramer Acetate28704-27-02A-3175151
Browse all Specialty Chemicals products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA