ARRY-380

Name: ARRY-380
Brand: 2A Biotech
SKU: 2A-1174992

CAS Number937265-83-3

SynonymsUNII-H32S1659ED; CS-0484; cc-595; Arry-380; ARRY-380 (analog )

Molecular FormulaC29H27O4N7S1

Molecular Weight569.64

Density1.4±0.1 g/cm3

Appearancepowder

Cat. No.: 2A-1174992 Purity:

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Quality Control of [ 937265-83-3 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	937265-83-3
Catalog No.	2A-1174992
Chinese Name	6-[5-[[[2-(甲磺酰基)乙基]氨基]甲基]-2-呋喃基]-N-[3-甲基-4-([1,2,4]三唑并[1,5-a]吡啶-7-氧基)苯基]-4-氨基喹唑啉
Synonyms	UNII-H32S1659ED; CS-0484; cc-595; Arry-380; ARRY-380 (analog )
Molecular Formula	C29H27O4N7S1
Molecular Weight	569.64
Density	1.4±0.1 g/cm3
Appearance	powder
Storage Condition	-20℃
Application	This product is an analogue of ARRY-380, a highly active HER2 inhibitor with an IC50 of 8 nM. It has the same inhibitory effect on cleaved p95-HER2 and is 500 times more inhibitory than EGFR.
PubChem ID	74370453
MDL Number	MFCD22420817
SMILES	Cc1cc(Nc2ncnc3ccc(-c4ccc(CNCCS(C)(=O)=O)o4)cc23)ccc1Oc1ccn2ncnc2c1
InChI	InChI=1S/C29H27N7O4S/c1-19-13-21(4-7-26(19)39-22-9-11-36-28(15-22)32-18-34-36)35-29-24-14-20(3-6-25(24)31-17-33-29)27-8-5-23(40-27)16-30-10-12-41(2,37)38/h3-9,11,13-15,17-18,30H,10,12,16H2,1-2H3,(H,31,33,35)
InChI Key	QVMNYGOVNWWFKF-UHFFFAOYSA-N
MSDS	msds/175385_1_937265_83_3.pdf
Transport Info	Product name: ARRY-380

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