CAS Number557756-85-1
SynonymsFmoc-15-Amino-4,7,10,13-Tetraoxapentadecanoic Acid; 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester; Fmoc-PEG4-propionic acid
Molecular FormulaC26H33NO8
Molecular Weight487.54
Purity>90%
Density1.219
Appearancesolid or viscous liquid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 557756-85-1 |
| Catalog No. | 2A-3174964 |
| Chinese Name | 5,8,11,14-四氧杂-2-氮杂十七烷二酸1-(9H-芴-9-基甲基)酯 |
| Synonyms | Fmoc-15-Amino-4,7,10,13-Tetraoxapentadecanoic Acid; 5,8,11,14-Tetraoxa-2-azaheptadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester; Fmoc-PEG4-propionic acid |
| Molecular Formula | C26H33NO8 |
| Molecular Weight | 487.54 |
| Purity | >90 |
| Density | 1.219 |
| Appearance | solid or viscous liquid |
| Storage Condition | 2-8°C, dry and sealed |
| Application | Fmoc-NH-PEG4-CH2CH2COOH is a degradable ADC linker for antibody drug conjugate (ADC) synthesis. |
| PubChem ID | 329823895 |
| MDL Number | MFCD06656472 |
| SMILES | OC(CCOCCOCCOCCOCCNC(OCC1C(C=CC=C2)=C2C3=C1C=CC=C3)=O)=O |
| InChI | 1S/C26H33NO8/c28-25(29)9-11-31-13-15-33-17-18-34-16-14-32-12-10-27-26(30)35-19-24-22-7-3-1-5-20(22)21-6-2-4-8-23(21)24/h1-8,24H,9-19H2,(H,27,30)(H,28,29) |
| InChI Key | NUHRPLKTAAVHCZ-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 51171641 |
| MSDS | msds/175356_1_557756_85_1.pdf |
| Bioactivity | Fmoc-NH-PEG4-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Target Cleavable In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14. Chemical & Physical Properties Density 1.219 Molecular Formula C26H33NO8 Molecular Weight 487.54200 Exact Mass 487.22100 PSA 112.55000 LogP 3.45710 InChIKey NUHRPLKTAAVHCZ-UHFFFAOYSA-N SMILES O=C(O)CCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc21 |
| Use of | Properties Name 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oic acid Synonym More Synonyms Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Cai P, et al. Synthesis of C3-Alkylated Indoles on DNA via Indolyl Alcohol Formation Followed by Metal-FreeTransfer Hydrogenation. Org Lett. 2019 Aug 14. Chemical & Physical Properties Molecular Formula C26H33NO8 Exact Mass 487.22100 PSA 112.55000 LogP 3.45710 InChIKey NUHRPLKTAAVHCZ-UHFFFAOYSA-N |
| Transport Info | Product name: Fmoc-PEG4-propionic acid |
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