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Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > 5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2Z)-2-butenedioate
5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2Z)-2-butenedioate structure, CAS 849643-15-8

5-[(Z)-(5-Fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2Z)-2-butenedioate

CAS Number849643-15-8

Synonymsqcr-24; cs-0649; SU14813 (maleate)

Molecular FormulaC27H31FN4O8

Molecular Weight442.49

Purity

Density

Boiling Point

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Cat. No.: 2A-1174441 Purity:
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Quality Control of [ 849643-15-8 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number849643-15-8
Catalog No.2A-1174441
Chinese NameSU14813马来酸盐
Synonymsqcr-24; cs-0649; SU14813 (maleate)
Molecular FormulaC27H31FN4O8
Molecular Weight442.49
Storage Condition2-8℃
ApplicationSU14813 maleate is a multi-target receptor tyrosine kinase inhibitor with IC50 values ​​of 50, 2, 4 and 15 nM for inhibiting VEGFR2, VEGFR1, PDGFRβ and KIT respectively.
PubChem ID16445171
MDL NumberC23H27FN4O4
SMILESCc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NCC(O)CN1CCOCC1.O=C(O)C=CC(=O)O
InChIInChI=1S/C23H27FN4O4.C4H4O4/c1-13-20(10-18-17-9-15(24)3-4-19(17)27-22(18)30)26-14(2)21(13)23(31)25-11-16(29)12-28-5-7-32-8-6-28;5-3(6)1-2-4(7)8/h3-4,9-10,16,26,29H,5-8,11-12H2,1-2H3,(H,25,31)(H,27,30);1-2H,(H,5,6)(H,7,8)/b18-10-;2-1-/t16-;/m0./s1
InChI KeyPQPBIMIFGPFTNF-IMEPDAPUSA-N
MSDSmsds/174794_1_849643_15_8.pdf
Transport InfoProduct name: SU14813 maleate
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