Dabrafenib Mesylate

Name: Dabrafenib Mesylate
Brand: 2A Biotech
SKU: 2A-1174410

CAS Number1195768-06-9

SynonymsTafinlar; UNII-B6DC89I63E; dabrafenib mesylate; GSK-2118436B; Dabrafenib (Mesylate)

Molecular FormulaC24H24F3N5O5S3

Molecular Weight615.668

Appearancewhite solid

Cat. No.: 2A-1174410 Purity:

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Quality Control of [ 1195768-06-9 ] SDS Specification MoL

Chemical & Physical Properties
CAS Number	1195768-06-9
Catalog No.	2A-1174410
Chinese Name	达帕菲尼甲磺酸盐
Synonyms	Tafinlar; UNII-B6DC89I63E; dabrafenib mesylate; GSK-2118436B; Dabrafenib (Mesylate)
Molecular Formula	C24H24F3N5O5S3
Molecular Weight	615.668
Appearance	white solid
Storage Condition	2-8℃
Application	Dabrafenib Mesylate is an ATP-competitive Raf inhibitor with IC50s of 5 nM and 0.6 nM for inhibiting C-Raf and B-RafV600E, respectively.
PubChem ID	85851636
SMILES	CC(C)(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2F)c(-c2ccnc(N)n2)s1.CS(=O)(=O)O
InChI	InChI=1S/C23H20F3N5O2S2.CH4O3S/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25;1-5(2,3)4/h4-11,31H,1-3H3,(H2,27,28,29);1H3,(H,2,3,4)
InChI Key	YKGMKSIHIVVYKY-UHFFFAOYSA-N
Transport Info	Product name: Dabrafenib mesylate

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