CAS Number578-76-7
Synonyms2-amino-7-methyl-3H-purin-6-one; 2-Amino-7-methyl-1,7-dihydro-6H-purin-6-one; 7-N-methylguanine; N(sup 7)-Methylguanine; 7-methyl-Guanine; Epiguanine; 2-Amino-7-methylhypoxanthine; N7-Methylguanine; 7-Methylguanine; 2-amino-7-methyl-1,7-dihydro-purin-6-one; 2-Amino-1,7-dihydro-7-methyl-6H-purin-6-one; GUANINE,7-METHYL; 2-Amino-6-hydroxy-7-methylpurine
Molecular FormulaC6H7N5O
Molecular Weight165.15
Purity≥98.0 (HPLC)%
Density1.8±0.1 g/cm3
Boiling Point481.4±37.0 °C at 760 mmHg
Melting Point370°C
EINECS209-431-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 578-76-7 |
| Catalog No. | 2A-1174158 |
| Chinese Name | 7-甲基鸟嘌呤 |
| Synonyms | 2-amino-7-methyl-3H-purin-6-one; 2-Amino-7-methyl-1,7-dihydro-6H-purin-6-one; 7-N-methylguanine; N(sup 7)-Methylguanine; 7-methyl-Guanine; Epiguanine; 2-Amino-7-methylhypoxanthine; N7-Methylguanine; 7-Methylguanine; 2-amino-7-methyl-1,7-dihydro-purin-6-one; 2-Amino-1,7-dihydro-7-methyl-6H-purin-6-one; GUANINE,7-METHYL; 2-Amino-6-hydroxy-7-methylpurine |
| Molecular Formula | C6H7N5O |
| Molecular Weight | 165.15 |
| Purity | ≥98.0 (HPLC) |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 481.4±37.0 °C at 760 mmHg |
| Melting Point | 370°C |
| Storage Condition | −20°C |
| Application | 7-Methylguanine is a metabolite of DNA methylation. It can be produced by methylation reagents and used as a probe for protein-DNA interactions and a key component of DNA sequencing methods. |
| EINECS | 209-431-0 |
| PubChem ID | 57652069 |
| MDL Number | MFCD00038003 |
| SMILES | Cn1cnc2N=C(N)NC(=O)c12 |
| InChI | 1S/C6H7N5O/c1-11-2-8-4-3(11)5(12)10-6(7)9-4/h2H,1H3,(H3,7,9,10,12) |
| InChI Key | FZWGECJQACGGTI-UHFFFAOYSA-N |
| Beilstein/REAXYS | 174245 |
| NACRES Code | NA.22 |
| UNSPSC | 12352005 |
| Hazard Symbols | transportation |
| MSDS | msds/174497_1_578_76_7.pdf |
| Bioactivity | 7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein-DNA interactions and a key component of DNA sequencing method. Related Catalog Natural Products >> Others Research Areas >> Others Target Human Endogenous Metabolite References [1]. Lee S, et al. Synthesis and structure of duplex DNA containing the genotoxic nucleobase lesion N7-methylguanine. J Am Chem Soc. 2008 Sep 3;130(35):11570-1. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 481.4±37.0 °C at 760 mmHg Melting Point 370°C Molecular Formula C6H7N5O Molecular Weight 165.153 Flash Point 244.9±26.5 °C Exact Mass 165.065063 PSA 89.59000 LogP -2.08 Vapour Pressure 0.0±1.3 mmHg at 25°C Index of Refraction 1.865 Storage condition −20°C |
| Use of | 7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein-DNA interactions and a key component of DNA sequencing method. Properties Name 2-amino-7-methyl-1,7-dihydro-6H-purin-6-one Synonym More Synonyms 7-Methylguanine Biological Activity Description 7-Methylguanine is a metabolite of DNA methylation. It can be generated by methylating agents, and used as a probe of protein-DNA interactions and a key component of DNA sequencing method. Related Catalog Natural Products >> Others Research Areas >> Others Human Endogenous Metabolite References Chemical & Physical Properties Molecular Formula C6H7N5O Exact Mass 165.065063 PSA 89.59000 LogP -2.08 Index of Refraction 1.865 |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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