![2-Chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-phenyl]-nicotinamide structure, CAS 1623101-11-0](/structures/180000/174320_1_1623101_11_0.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1623101-11-0 |
| Catalog No. | 2A-1173986 |
| Chinese Name | VU0483605 |
| Synonyms | vu0483605 |
| Molecular Formula | C20H10O3N3Cl3 |
| Molecular Weight | 446.68 |
| Density | 1.6±0.1 g/cm3 |
| Storage Condition | 2-8°C |
| Application | VU0483605 is a potent, brain-penetrating mGlu1 receptor-positive allosteric modulator (PAM). VU0483605 exhibits excellent mGlu1 PAM activity in both humans and rats, with EC50 values of 390 and 356 |
| PubChem ID | 252451368 |
| MDL Number | MFCD29770792 |
| SMILES | O=C(Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1)c1ncccc1Cl |
| InChI | InChI=1S/C20H10Cl3N3O3/c21-12-4-1-3-11-16(12)20(29)26(19(11)28)15-7-6-10(9-14(15)23)25-18(27)17-13(22)5-2-8-24-17/h1-9H,(H,25,27) |
| InChI Key | HJQXPBKPTGWZCF-UHFFFAOYSA-N |
| MSDS | msds/174320_1_1623101_11_0.pdf |
| Transport Info | Product name: 2-Chloro-N-[3-chloro-4-(4-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)phenyl]nicotinamide |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 4-Chloro-quinazolin-8-ol | 154288-08-1 | 2A-1173980 |
| 2-Cyano-4,4-dimethyl-pent-2-enoic acid | 88319-37-3 | 2A-1173982 |
| 2-[4-(6-Benzyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl]-propan-2-ol | 1204975-42-7 | 2A-1173983 |
| 3-Hydroxy-2-phenyl-propanamide | 56598-62-0 | 2A-1173984 |
| (4-Methoxy-phenyl)-(6-methoxy-quinazolin-4-yl)-amine hydrochloride | 338736-46-2 | 2A-1173985 |
| 2-Chloro-5-iodonicotinic acid | 59782-86-4 | 2A-1173988 |
| 1-bromo-3,3-dimethyl-2-butanol | 1438-13-7 | 2A-1173829 |
| 4-CHLORO-D-PHENYLALANINE HYDROCHLORIDE | 147065-05-2 | 2A-1173990 |
| Cbz-4-Bromo-D-Phenylalanine | 1100357-99-0 | 2A-1173992 |
| Cbz-4-Nitro-D-Phenylalanine | 117402-88-7 | 2A-1173994 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA