8-Hydroxy Efavirenz

Name: 8-Hydroxy Efavirenz
Brand: 2A Biotech
SKU: 2A-1173808

CAS Number205754-33-2

Synonyms8-HYDROXY EFAVIRENZ; 6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one

Molecular FormulaC14H9ClF3NO3

Molecular Weight331.674

Purity98.00%

Density1.6±0.1 g/cm3

Boiling Point373.6±42.0 °C at 760 mmHg

Melting Point144-154ºC

Cat. No.: 2A-1173808 Purity: 98.00%

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Quality Control of [ 205754-33-2 ] Purity: 98.00% SDS Specification MoL

Chemical & Physical Properties
CAS Number	205754-33-2
Catalog No.	2A-1173808
Chinese Name	8-羟基依法韦仑
Synonyms	8-HYDROXY EFAVIRENZ; 6-Chloro-4-(cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one
Molecular Formula	C14H9ClF3NO3
Molecular Weight	331.674
Purity	98.00
Density	1.6±0.1 g/cm3
Boiling Point	373.6±42.0 °C at 760 mmHg
Melting Point	144-154ºC
Storage Condition	-20°C, sealed, dry
Application	8-hydroxyefavirenz (8-OH-EFV) is the main metabolite of efavirenz (HY-10572). 8-Hydroxyefavirenz induces apoptosis in primary human hepatocytes via a JNK- and BimEL-dependent mechanism. 8-Hydroxyefavi
PubChem ID	647267
SMILES	O=C1Nc2c(O)cc(Cl)cc2C(C#CC2CC2)(C(F)(F)F)O1
InChI	InChI=1S/C14H9ClF3NO3/c15-8-5-9-11(10(20)6-8)19-12(21)22-13(9,14(16,17)18)4-3-7-1-2-7/h5-7,20H,1-2H2,(H,19,21)/t13-/m0/s1
InChI Key	OOVOMPCQLMFEDT-ZDUSSCGKSA-N
Transport Info	Product Name: 8-Hydroxyefavirenz

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