
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1051375-16-6 |
| Catalog No. | 2A-1173023 |
| Chinese Name | 度鲁特韦 |
| Synonyms | GSK 1349572; S-349572; Tivicay; Dolutegravir; GSK1349572 |
| Molecular Formula | C20H19F2N3O5 |
| Molecular Weight | 419.38 |
| Purity | ≥98 (HPLC) |
| Density | 1.53 g/cm3 |
| Boiling Point | 669.0±55.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | Room temperature, dry, sealed |
| Application | Dolutegravir is a second-generation HIV integrase strand transfer inhibitor (INSTI) with an IC50 of 2.7 nM. |
| SMILES | C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O |
| InChI | 1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1 |
| InChI Key | RHWKPHLQXYSBKR-BMIGLBTASA-N |
| NACRES Code | NA.41 |
| UNSPSC | 51101500 |
| Transport Info | Product name: Dolutegravir (GSK1349572) |
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| N/A | 679809-76-8 | 2A-1173025 |
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