CAS Number2002-35-9
SynonymsN-6-methyl-2'-deoxyribofuranosil adenine; N6-Methyl-2'-desoxy-adenosin; N6-Methyldeoxyadenosine; 2'-Deoxy-N6-methylado; Adenosine,2'-deoxy-N-methyl; N6-Methyl-2'-deoxyadenosine; 2'-deoxy-N6-methyladenosine; N6-methyl-2'-deoxy-adenosine
Molecular FormulaC11H15N5O3
Molecular Weight265.27
Purity≥98 (TLC)%
Density1.72g/cm3
Boiling Point603.6ºC at 760mmHg
Appearancepowder
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2002-35-9 |
| Catalog No. | 2A-1172956 |
| Chinese Name | N[6]-甲基-2'-脱氧腺苷 |
| Synonyms | N-6-methyl-2'-deoxyribofuranosil adenine; N6-Methyl-2'-desoxy-adenosin; N6-Methyldeoxyadenosine; 2'-Deoxy-N6-methylado; Adenosine,2'-deoxy-N-methyl; N6-Methyl-2'-deoxyadenosine; 2'-deoxy-N6-methyladenosine; N6-methyl-2'-deoxy-adenosine |
| Molecular Formula | C11H15N5O3 |
| Molecular Weight | 265.27 |
| Purity | ≥98 (TLC) |
| Density | 1.72g/cm3 |
| Boiling Point | 603.6ºC at 760mmHg |
| Appearance | powder |
| Water Solubility | Soluble in water |
| Storage Condition | −20°C |
| Application | N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analog. Purine nucleoside analogues have broad antitumor activity and target indolent lymphoid malignancies. The anti-cancer mechanism in this proc |
| HTC | 29349990 |
| PubChem ID | 24896727 |
| MDL Number | MFCD00055999 |
| SMILES | CNc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3 |
| InChI | 1S/C11H15N5O3/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(18)7(3-17)19-8/h4-8,17-18H,2-3H2,1H3,(H,12,13,14)/t6-,7+,8+/m0/s1 |
| InChI Key | DYSDOYRQWBDGQQ-XLPZGREQSA-N |
| NACRES Code | NA.51 |
| UNSPSC | 41106305 |
| Hazard Symbols | transportation |
| MSDS | msds/173244_1_2002_35_9.pdf |
| Bioactivity | N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Density 1.72g/cm3 Boiling Point 603.6ºC at 760mmHg Molecular Formula C11H15N5O3 Molecular Weight 265.27 Flash Point 318.8ºC Exact Mass 265.11700 PSA 105.32000 Appearance of Characters Powder | White to Off-white Vapour Pressure 2.03E-15mmHg at 25°C Index of Refraction 1.78 InChIKey DYSDOYRQWBDGQQ-XLPZGREQSA-N SMILES CNc1ncnc2c1ncn2C1CC(O)C(CO)O1 Storage condition −20°C Water Solubility Soluble in water |
| Use of | N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Properties Name (2R,3S,5R)-2-(hydroxymethyl)-5-[6-(methylamino)purin-9-yl]oxolan-3-ol Synonym More Synonyms n6-methyl-2'-deoxy-adenosine Biological Activity Description N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others References [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. Chemical & Physical Properties Molecular Formula C11H15N5O3 Exact Mass 265.11700 PSA 105.32000 Appearance of Characters Powder | White to Off-white Index of Refraction 1.78 InChIKey DYSDOYRQWBDGQQ-XLPZGREQSA-N Water Solubility Soluble in water |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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