
CAS Number109511-58-2
Synonyms(2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanylmethylidene]butanedinitrile; U 0126; (2Z,3Z)-Bis{amino[(2-aminophenyl)sulfanyl]methylene}succinonitrile; (2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylidene}butanedinitrile; U0126; U-0126
Molecular FormulaC18H16N6S2
Molecular Weight403.52
Purity≥98 (HPLC)%
Density1.4±0.1 g/cm3
Boiling Point565.1±50.0 °C at 760 mmHg
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 109511-58-2 |
| Catalog No. | 2A-1172884 |
| Chinese Name | 1,4-二氨基-2,3-二氰基-1,4-双(邻氨基苯巯基)丁二烯 |
| Synonyms | (2Z,3Z)-2,3-bis[amino-(2-aminophenyl)sulfanylmethylidene]butanedinitrile; U 0126; (2Z,3Z)-Bis{amino[(2-aminophenyl)sulfanyl]methylene}succinonitrile; (2Z,3Z)-bis{amino[(2-aminophenyl)sulfanyl]methylidene}butanedinitrile; U0126; U-0126 |
| Molecular Formula | C18H16N6S2 |
| Molecular Weight | 403.52 |
| Purity | ≥98 (HPLC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 565.1±50.0 °C at 760 mmHg |
| Appearance | solid |
| Storage Condition | -20°C, sealed, dry |
| Application | U0126 is a potent, non-ATP competitive, selective MEK1 and MEK2 inhibitor with IC50 of 72 nM and 58 nM respectively. U0126-EtOH is an inhibitor of autophagy and mitophagy. |
| PubChem ID | 813618 |
| MDL Number | MFCD09971039 |
| SMILES | S(c2c(cccc2)N)\C(=C(\C(=C(\Sc1c(cccc1)N)/N)\C#N)/C#N)\N |
| InChI | 1S/C18H16N6S2/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22/h1-8H,21-24H2/b17-11+,18-12+ |
| InChI Key | DVEXZJFMOKTQEZ-JYFOCSDGSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/173169_1_109511_58_2.pdf |
| Transport Info | Product name: U0126 |
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