EN
0
Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > N-Succinimidyl 11-(maleimido)undecanoate
N-Succinimidyl 11-(maleimido)undecanoate structure, CAS 87981-04-2

N-Succinimidyl 11-(maleimido)undecanoate

CAS Number87981-04-2

Synonyms(2,5-dioxopyrrolidin-1-yl) 11-(2,5-dioxopyrrol-1-yl)undecanoate; 1-{11-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-11-oxoundecyl}-1H-pyrrole-2,5-dione

Molecular FormulaC19H26O6N2

Molecular Weight378.43

Purity

Density1.3±0.1 g/cm3

Boiling Point520.4±42.0 °C at 760 mmHg

Melting Point

Flash Point

Appearance

EINECS

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-1172826 Purity:
Change View

Please Login or Create an Account to: See VlP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

Inquiry

Quality Control of [ 87981-04-2 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number87981-04-2
Catalog No.2A-1172826
Chinese Name11-马来酰亚胺十一烷酸 N-琥珀酰亚胺酯
Synonyms(2,5-dioxopyrrolidin-1-yl) 11-(2,5-dioxopyrrol-1-yl)undecanoate; 1-{11-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-11-oxoundecyl}-1H-pyrrole-2,5-dione
Molecular FormulaC19H26O6N2
Molecular Weight378.43
Density1.3±0.1 g/cm3
Boiling Point520.4±42.0 °C at 760 mmHg
Storage Condition2~8°C, sealed
ApplicationMaleimide-C10-NHS ester is a PROTAC linker, belonging to the alkyl/ether class. Can be used to synthesize PROTAC molecules.
PubChem ID7542907
MDL NumberMFCD00467873
SMILESO=C(CCCCCCCCCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O
InChIInChI=1S/C19H26N2O6/c22-15-10-11-16(23)20(15)14-8-6-4-2-1-3-5-7-9-19(26)27-21-17(24)12-13-18(21)25/h10-11H,1-9,12-14H2
InChI KeySGNVTRHWJGTNKV-UHFFFAOYSA-N
MSDSmsds/173111_1_87981_04_2.pdf
BioactivityMaleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Target Alkyl/ether In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 520.4±42.0 °C at 760 mmHg Molecular Formula C19H26N2O6 Molecular Weight 378.419 Flash Point 268.5±27.9 °C Exact Mass 378.179077 PSA 101.06000 LogP 1.84 Vapour Pressure 0.0±1.4 mmHg at 25°C Index of Refraction 1.552 InChIKey SGNVTRHWJGTNKV-UHFFFAOYSA-N SMILES O=C(CCCCCCCCCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O
Use ofMaleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 11-Maleimidoundecanoic Acid N-Succinimidyl Ester Synonym More Synonyms Maleimide-C10-NHS ester Biological Activity Description Maleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Alkyl/ether In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1] References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. Chemical & Physical Properties Molecular Formula C19H26N2O6 Exact Mass 378.179077 PSA 101.06000 Index of Refraction 1.552 InChIKey SGNVTRHWJGTNKV-UHFFFAOYSA-N
Transport InfoProduct name: Purity: 98.0%
MSDS Transport InfoModule 14. Shipping information United Nations classification: inconsistent with United Nations classification standards UN number: not specified 11-Maleimidodecanoic acid succinimidyl ester Modification number: 4
Related Products in Specialty Chemicals
DIETHYL N-BUTANEPHOSPHONATE2404-75-32A-1172819
1,2-DICARBOBENZYLOXYHYDRAZINE5394-50-32A-1172820
2,3,4,5,6-PENTAFLUOROPHENYL 4-NITROBENZENESULFONATE244633-31-62A-1172822
(E)-N-((((9H-fluoren-9-yl)methoxy)carbonyl)oxy)-2-amino-2-oxoacetimidoyl cyanide1370440-28-02A-1172824
TRIS(2-CYANOETHYL)PHOSPHINE4023-53-42A-1172825
6-MALEIMIDOCAPROIC ACID SULFO-N-SUCCINIMIDYL ESTER215312-86-02A-1172827
1,2-BISMALEIMIDOETHANE5132-30-92A-1172828
Methyl 4-(diethylcarbaMoyl)benzoate122357-96-42A-1172831
2-(4-BroMo-phenyl)-1,10-phenanthroline149054-39-72A-0172881
2-Chloro-9-phenyl-1,10-phenanthroline1937210-90-62A-1172882
Browse all Specialty Chemicals products »
Contact Us

Phone:

630-322-8886

630-322-8887

Email:

[email protected]

Office Locations:

Chicago, IL, USA

San Francisco, CA, USA