| Chemical & Physical Properties | |
|---|---|
| CAS Number | 152305-87-8 |
| Catalog No. | 2A-1172818 |
| Chinese Name | 1-乙酰氧基-2,5-二氧代吡咯烷-3-磺酸 |
| Synonyms | Sulfo-nhs-acetate; BIM103; Sulfosuccinimidyl acetate; 3-Pyrrolidinesulfonicacid,1-(acetyloxy)-2,5-dioxo; 1-Acetoxy-2,5-dioxopyrrolidine-3-sulfonic acid |
| Molecular Formula | C6H7O7N1S1 |
| Molecular Weight | 237.19 |
| Density | 1.8g/cm3 |
| Storage Condition | 2-8°C, dry, sealed |
| Application | Sulfo-NHS-Acetate is a PROTAC linker, belonging to the alkyl chain class. Can be used to synthesize PROTAC molecules. |
| HTC | 2925190090 |
| PubChem ID | 10241876 |
| MDL Number | MFCD01861959 |
| SMILES | CC(=O)ON1C(=O)CC(S(=O)(=O)O)C1=O |
| InChI | InChI=1S/C6H7NO7S/c1-3(8)14-7-5(9)2-4(6(7)10)15(11,12)13/h4H,2H2,1H3,(H,11,12,13) |
| InChI Key | MDUQWFYJHRLNRN-UHFFFAOYSA-N |
| MSDS | msds/173103_1_152305_87_8.pdf |
| Use of | Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 1-acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid Synonym More Synonyms sulfo-NHS-acetate Biological Activity Description Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker Alkyl-Chain In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C6H7NO7S Exact Mass 236.99400 PSA 126.43000 Index of Refraction 1.583 InChIKey MDUQWFYJHRLNRN-UHFFFAOYSA-N Safety Information Hazard Codes Xi HS Code 2925190090 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
| Related Products in Nutritional Ingredients | ||
|---|---|---|
| TETRAAMMINEPALLADIUM(II) NITRATE | 13601-08-6 | 2A-1172326 |
| Bucladesine calcium salt | 2A-1172394 | 2A-1172394 |
| N-(1-Oxohexadecyl)-L-glutaMic Acid tert-Butyl Ester | 536721-25-2 | 2A-1172503 |
| N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-(2-pyridinyl)-beta-alanine ethyl ester hydrochloride | 211914-50-0 | 2A-1172611 |
| GAMMA-METHYL-L-LEUCINE | 57224-50-7 | 2A-1172659 |
| 1,4-DIBENZOYL-2,3:5,6-DI-O-ISOPROPYLIDENE-MYO-INOSITOL | 99756-37-3 | 2A-1173393 |
| 1,2:4,5-Di-O-isopropylidene-D,L-myo-inositol | 98974-89-1 | 2A-1173394 |
| DL-ALPHA-TOCOPHEROL ACETATE | 52225-20-4 | 2A-1173744 |
| DL-alpha-Tocopherol | 21-59-0 | 2A-1173745 |
| Cbz-4-Bromo-L-Phenylalanine | 158069-49-9 | 2A-1173996 |
| Browse all Nutritional Ingredients products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS