| Chemical & Physical Properties | |
|---|---|
| CAS Number | 473278-54-5 |
| Catalog No. | 2A-1172760 |
| Chinese Name | 2′-O-(2-甲氧基乙基)鸟苷 |
| Synonyms | 2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-(2-methoxyethoxy)oxolan-2-yl]-3H-purin-6-one; 2'-O-(2-Methoxyethyl)guanosine |
| Molecular Formula | C13H19O6N5 |
| Molecular Weight | 341.32 |
| Density | 1.811g/cm3 |
| Appearance | solid |
| Storage Condition | 2-8°C, protected from light, dry |
| Application | 2'-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG) is a 2'-O-methoxyethyl-modified nucleoside that can be generated by the enzymatic conversion (adenosine deaminase) of 2'-O-(2-methoxyethyl)-2,6-diaminopuri |
| HTC | 2909199090 |
| PubChem ID | 16087132 |
| MDL Number | MFCD02682962 |
| SMILES | COCCOC1C(O)C(CO)OC1n1cnc2c(=O)[nH]c(N)nc21 |
| InChI | InChI=1S/C13H19N5O6/c1-22-2-3-23-9-8(20)6(4-19)24-12(9)18-5-15-7-10(18)16-13(14)17-11(7)21/h5-6,8-9,12,19-20H,2-4H2,1H3,(H3,14,16,17,21)/t6-,8-,9-,12-/m1/s1 |
| InChI Key | DLLBJSLIKOKFHE-WOUKDFQISA-N |
| MSDS | msds/173043_1_473278_54_5.pdf |
| Use of | 2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA[1][2]. Properties Name 2'-O-(2-Methoxyethyl)-guanosine Synonym More Synonyms 2′-O-(2-Methoxyethyl)guanosine Biological Activity Description 2′-O-(2-Methoxyethyl)guanosine (2'-O-MOE-rG), a 2′-O-methoxyethyl-modified nucleoside, can be produced by enzymatic conversion (adenosine deaminase) from 2′-O-(2-methoxyethyl)-2,6-diaminopurine riboside. 2′-O-(2-Methoxyethyl)guanosine neither effectively phosphorylated by cytosolic nucleoside kinases, nor are they incorporated into cellular DNA or RNA[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. McPherson AK, et, al. An Improved Process for the Manufacture of 5′-O-(4,4′-Dimethoxytrityl)-N2-isobutyryl-2′-O-(2-methoxyethyl)guanosine. Org. Process Res. Dev. 2020, 24, 11, 2583-2590. Chemical & Physical Properties Molecular Formula C13H19N5O6 Exact Mass 341.13400 PSA 157.74000 Index of Refraction 1.745 InChIKey DLLBJSLIKOKFHE-WOUKDFQISA-N Safety Information Hazard Codes Xi HS Code 2909199090 Precursor & DownStream Precursor 5 CAS#:1061667-18-2 2'-methoxyethyl... CAS#:6482-24-2 1-Bromo-2-metho... CAS#:2096-10-8 2-Aminoadenosine CAS#:118-00-3 DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0% |
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