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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > DROFENINE HYDROCHLORIDE
DROFENINE HYDROCHLORIDE structure, CAS 548-66-3

DROFENINE HYDROCHLORIDE

CAS Number548-66-3

Synonymscyclovegantine; hexahydroadiphenine; cycloadiphenine; Cyclovegantin*Hydrochlorid; Cycloadiphenin*Hydrochlorid; Drofeninhydrochlorid; it-19; Cyclohexyl-phenyl-essigsaeure-(2-diaethylamino-aethylester),Hydrochlorid; DROFENINE HCL; cyclohexyl-phenyl-acetic acid-(2-diethylamino-ethyl ester),hydrochloride; trasentinh; DrofeninHCl

Molecular FormulaC20H32ClNO2

Molecular Weight353.92700

Purity

Density

Boiling Point417.4ºC at 760mmHg

Melting Point145-147°

Flash Point

Appearancepowder

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-4172669 Purity:
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Quality Control of [ 548-66-3 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number548-66-3
Catalog No.2A-4172669
Chinese Name盐酸六氢芬宁
Synonymscyclovegantine; hexahydroadiphenine; cycloadiphenine; Cyclovegantin*Hydrochlorid; Cycloadiphenin*Hydrochlorid; Drofeninhydrochlorid; it-19; Cyclohexyl-phenyl-essigsaeure-(2-diaethylamino-aethylester),Hydrochlorid; DROFENINE HCL; cyclohexyl-phenyl-acetic acid-(2-diethylamino-ethyl ester),hydrochloride; trasentinh; DrofeninHCl
Molecular FormulaC20H32ClNO2
Molecular Weight353.92700
Boiling Point417.4ºC at 760mmHg
Melting Point145-147°
Appearancepowder
Storage Condition2-8°C
ApplicationDrofenine hydrochloride is a potent competitive cholinesterase inhibitor with a ki value of 3 uM.
PubChem ID546277
SMILESCCN(CC)CCOC(=O)C(c1ccccc1)C1CCCCC1.Cl
InChIInChI=1S/C20H31NO2.ClH/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18;/h5,7-8,11-12,18-19H,3-4,6,9-10,13-16H2,1-2H3;1H
InChI KeyWIELVDXKOYPANK-UHFFFAOYSA-N
Hazard Symbolstransportation
MSDSmsds/172950_2_548_66_3.pdf
BioactivityDrofenine hydrochloride is a potent competitive inhibitor of BChE, and the ki values of Drofenine is calculated to be 3 uM.IC50 value: 3 uM (ki)Target: BChEBenactyzine is widely used anticholinergic drugs, acts on smooth muscle to stop muscle spasms. Related Catalog Signaling Pathways >> Neuronal Signaling >> AChE Research Areas >> Neurological Disease References [1]. Bodur E, et al. Inhibition effects of benactyzine and drofenine on human serum butyrylcholinesterase. Arch Biochem Biophys. 2001 Feb 1;386(1):25-29. Chemical & Physical Properties Boiling Point 417.4ºC at 760mmHg Melting Point 145-147° Molecular Formula C20H32ClNO2 Molecular Weight 353.92700 Flash Point 124.6ºC Exact Mass 353.21200 PSA 29.54000 LogP 5.03750 InChIKey WIELVDXKOYPANK-UHFFFAOYSA-N SMILES CCN(CC)CCOC(=O)C(c1ccccc1)C1CCCCC1.Cl Storage condition 2-8°C
Use ofDrofenine hydrochloride is a potent competitive inhibitor of BChE, and the ki values of Drofenine is calculated to be 3 uM.IC50 value: 3 uM (ki)Target: BChEBenactyzine is widely used anticholinergic drugs, acts on smooth muscle to stop muscle spasms. Properties Name drofenine hydrochloride Synonym More Synonyms Drofenine hydrochloride Biological Activity Description Drofenine hydrochloride is a potent competitive inhibitor of BChE, and the ki values of Drofenine is calculated to be 3 uM.IC50 value: 3 uM (ki)Target: BChEBenactyzine is widely used anticholinergic drugs, acts on smooth muscle to stop muscle spasms. Related Catalog Signaling Pathways >> Neuronal Signaling >> AChE Research Areas >> Neurological Disease References [1]. Bodur E, et al. Inhibition effects of benactyzine and drofenine on human serum butyrylcholinesterase. Arch Biochem Biophys. 2001 Feb 1;386(1):25-29. Chemical & Physical Properties Exact Mass 353.21200 PSA 29.54000 LogP 5.03750 InChIKey WIELVDXKOYPANK-UHFFFAOYSA-N
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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