| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1114544-31-8 |
| Catalog No. | 2A-1172625 |
| Chinese Name | 普纳替尼-单盐酸盐 |
| Synonyms | Iclusig (TN); UNII-96R6PU3D8J; Ponatinib hydrochloride (USAN); AP 24534 hydrochloride; Ponatinib hydrochloride; 96R6PU3D8J; Ponatinib HCl |
| Molecular Formula | C29H28ClF3N6O |
| Molecular Weight | 569.02 |
| Purity | 98% |
| Appearance | solid |
| Storage Condition | 2-8°C, protected from light |
| Application | Bonatinil (AP24534) hydrochloride is the hydrochloride salt of ponatinil. Bonatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM for Abl |
| PubChem ID | 85390727 |
| SMILES | Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2cccnn12.Cl |
| InChI | InChI=1S/C29H27F3N6O.ClH/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37;/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39);1H |
| InChI Key | BWTNNZPNKQIADY-UHFFFAOYSA-N |
| Transport Info | Product Name: Ponatinib hydrochloride |
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| 2-METHOXYESTRADIOL | 362-07-2 | 2A-1173145 |
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