![(2R)-2-({[3,5-bis(trifluoromethyl)phenyl]carbamothioyl}amino)-N-(2,4-difluorophenyl)-2-phenylacetamide structure, CAS 2101517-69-3](/structures/180000/172522_2_2101517_69_3.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2101517-69-3 |
| Catalog No. | 2A-1172276 |
| Chinese Name | BL-918 |
| Synonyms | Target; References |
| Molecular Formula | C23H15F8N3OS |
| Molecular Weight | 533.437 |
| Purity | 98.00 |
| Density | 1.5±0.1 g/cm3 |
| Appearance | solid |
| Storage Condition | 2-8°C, sealed |
| Application | BL-918 is a small molecule activator of ULK1 with an EC50 of 24 nM (kinase activity of 243% at 100 nM). It induces autophagy through the ULK complex in SH-SY5Y cells; it shows a cytoprotective effect |
| PubChem ID | 404983030 |
| SMILES | O=C(Nc1ccc(F)cc1F)C(NC(=S)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1 |
| InChI | InChI=1S/C23H15F8N3OS/c24-15-6-7-18(17(25)11-15)33-20(35)19(12-4-2-1-3-5-12)34-21(36)32-16-9-13(22(26,27)28)8-14(10-16)23(29,30)31/h1-11,19H,(H,33,35)(H2,32,34,36)/t19-/m1/s1 |
| InChI Key | BDBWQANRZRCMMD-LJQANCHMSA-N |
| Transport Info | Product name: BL-918 |
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