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2',7'-DICHLOROFLUORESCEIN

Name: 2',7'-DICHLOROFLUORESCEIN
Brand: 2A Biotech
SKU: 2A-1171928

CAS Number76-54-0

SynonymsEINECS 200-968-6; dichlorofluorescein; 2',7'-dichloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one; 2',7'-Dichloro-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one; 2',7'-Dichlorofluorescein; MFCD00005047

Molecular FormulaC20H10Cl2O5

Molecular Weight401.196

Purity98.00%%

Density1.8±0.1 g/cm3

Boiling Point634.4±55.0 °C at 760 mmHg

Melting Point280 °C (dec.)(lit.)

AppearanceOrange-yellow solid

MSDSChinese English

Symbol

Signal WordWarning

Cat. No.: 2A-1171928 Purity: 98.00%%

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Quality Control of [ 76-54-0 ] Purity: 98.00%% SDS Specification MoL

Chemical & Physical Properties
CAS Number	76-54-0
Catalog No.	2A-1171928
Chinese Name	2',7'-二氯荧光素
Synonyms	EINECS 200-968-6; dichlorofluorescein; 2',7'-dichloro-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one; 2',7'-Dichloro-3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one; 2',7'-Dichlorofluorescein; MFCD00005047
Molecular Formula	C20H10Cl2O5
Molecular Weight	401.196
Purity	98.00%
Density	1.8±0.1 g/cm3
Boiling Point	634.4±55.0 °C at 760 mmHg
Melting Point	280 °C (dec.)(lit.)
Appearance	Orange-yellow solid
Water Solubility	Soluble in: sodium hydroxide aqueous solution; sli
Storage Condition	This product should be sealed and stored in a cool
Application	2',7'-Dichlorofluorescein is used as a fluorescent probe (Ex=496nm, Em=525nm) for reactive oxygen species (ROS) measurement [1].
HTC	3204200000
PubChem ID	3138178
SMILES	O=C1OC2(c3cc(Cl)c(O)cc3Oc3cc(O)c(Cl)cc32)c2ccccc21
InChI	InChI=1S/C20H10Cl2O5/c21-13-5-11-17(7-15(13)23)26-18-8-16(24)14(22)6-12(18)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,23-24H
InChI Key	VFNKZQNIXUFLBC-UHFFFAOYSA-N
Hazard Symbols	3.0
MSDS	msds/172148_2_76_54_0.pdf
Bioactivity	2',7'-Dichlorofluorescein acts as a fluorescent probe (Ex=496 nm and Em=525 nm) for reactive oxygen species (ROS) measurement[1]. Related Catalog Research Areas >> Cancer References [1]. Reiniers MJ, et al. Preparation and Practical Applications of 2',7'-Dichlorodihydrofluorescein in Redox Assays. Anal Chem. 2017 Apr 4;89(7):3853-3857. [2]. Xiuping Chen, et al. 2',7'-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radic Res. 2010 Jun;44(6):587-604. Chemical & Physical Properties Density 1.8±0.1 g/cm3 Boiling Point 634.4±55.0 °C at 760 mmHg Melting Point 280 °C (dec.)(lit.) Molecular Formula C20H10Cl2O5 Molecular Weight 401.196 Flash Point 337.4±31.5 °C Exact Mass 399.990540 PSA 75.99000 LogP 4.10 Vapour Pressure 0.0±1.9 mmHg at 25°C Index of Refraction 1.797 InChIKey VFNKZQNIXUFLBC-UHFFFAOYSA-N SMILES O=C1OC2(c3cc(Cl)c(O)cc3Oc3cc(O)c(Cl)cc32)c2ccccc21 Stability Stable. Incompatible with strong oxidizing agents.
Use of	2',7'-Dichlorofluorescein acts as a fluorescent probe (Ex=496 nm and Em=525 nm) for reactive oxygen species (ROS) measurement[1]. Properties Articles63 Name 2',7'-dichlorofluorescein Synonym More Synonyms dichlorofluorescein Biological Activity Description 2',7'-Dichlorofluorescein acts as a fluorescent probe (Ex=496 nm and Em=525 nm) for reactive oxygen species (ROS) measurement[1]. Related Catalog Research Areas >> Cancer References [1]. Reiniers MJ, et al. Preparation and Practical Applications of 2',7'-Dichlorodihydrofluorescein in Redox Assays. Anal Chem. 2017 Apr 4;89(7):3853-3857. [2]. Xiuping Chen, et al. 2',7'-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radic Res. 2010 Jun;44(6):587-604. Chemical & Physical Properties Exact Mass 399.990540 PSA 75.99000 Index of Refraction 1.797 InChIKey VFNKZQNIXUFLBC-UHFFFAOYSA-N Stability Stable. Incompatible with strong oxidizing agents.
Tax Rebate	13.0%
Supervision	None. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport Info	Shipping Name: UN
MSDS Transport Info	Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Danger Regulations: 1219 International Maritime Danger Regulations: 1219 International Air Transport Danger Regulations: 1219 14.2 United Nations shipping name European Land Transport Dangerous Regulations: ISOPROPANOL, solution IMDG Code: ISOPROPANOL, solution IMDG: Isopropanol, solution, solution 14.3 Transport hazard categories European land transport Dangerous Regulations: 3 International sea transport Dangerous Regulations: 3 International air transport Dangerous Regulations: 3 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available

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2',7'-DICHLOROFLUORESCEIN

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