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Home > Products > Specialty & Industrial Chemicals > Specialty Chemicals > (+)-[[(2Z)-[2-[[(2S 3S)-2-[[(AMINOCARBON
(+)-[[(2Z)-[2-[[(2S 3S)-2-[[(AMINOCARBON structure, CAS 86832-68-0

(+)-[[(2Z)-[2-[[(2S 3S)-2-[[(AMINOCARBON

CAS Number86832-68-0

SynonymsAmasulin (TN); Carumonam; CRMN; MFCD00875847; Mobactam; Carumonam disodium salt; Amasulin

Molecular FormulaC12H14N6O10S2

Molecular Weight466.404

Purity98%%

Density2.1±0.1 g/cm3

Boiling Point

Melting Point250ºC (dec.)(lit.)

Flash Point

Appearance

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Cat. No.: 2A-1171263 Purity: 98%%
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Quality Control of [ 86832-68-0 ] Purity: 98%% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number86832-68-0
Catalog No.2A-1171263
Chinese Name(+)-[[2Z-[2-[[(2S,3S)-2-[[(氨基羰基)氧代]甲基]-4-氧-1-硫代-3-吖丁啶基]氨基]-1-(2-氨基-4-噻唑基)-2-氧代亚乙基]氨基]氧代]乙酸二钠盐
SynonymsAmasulin (TN); Carumonam; CRMN; MFCD00875847; Mobactam; Carumonam disodium salt; Amasulin
Molecular FormulaC12H14N6O10S2
Molecular Weight466.404
Purity98%
Density2.1±0.1 g/cm3
Melting Point250ºC (dec.)(lit.)
Storage ConditionKeep the container sealed and stored in a cool, dr
ApplicationCalunan disodium is a powerful antibiotic. Calunan disodium exhibits antibacterial activity. Calunan disodium induces epilepsy[1][2].
SMILESNC(=O)OCC1C(NC(=O)C(=NOCC(=O)[O-])c2csc(N)n2)C(=O)N1S(=O)(=O)[O-].[Na+].[Na+]
InChIInChI=1S/C12H14N6O10S2.2Na/c13-11-15-4(3-29-11)7(17-28-2-6(19)20)9(21)16-8-5(1-27-12(14)23)18(10(8)22)30(24,25)26;;/h3,5,8H,1-2H2,(H2,13,15)(H2,14,23)(H,16,21)(H,19,20)(H,24,25,26);;/q;2*+1/p-2/b17-7-;;/t5-,8+;;/m1../s1
InChI KeyBGGXRVPCJUKHTQ-REOVRMSNSA-L
BioactivityCarumonam disodium is a potent antibiotic. Carumonam disodium shows antibacterial activity. Carumonam disodium induces seizure[1][2]. (cefazolin sensitive), Escherichia coli (cefazolin resistant), Klebsiella pneumoniae (cefazolin sensitive), Klebsiella pneumoniae (cefazolin resistant), Klebsiella oxytoca, Enterobacter cloacae, Serratia marcescens (gentamicin sensitive), Serratia marcescens (gentamicin resistant), Proteus vulgaris, Proteus mirabilis, Proteus The MIC90 values of morganii, Proteus rettgeri, and Proteus inconstans are 0.2, 3.13, 0.2, 0.39, 0.2, 6.25, 0.2, 3.13, 0.05, 0.025, 0.78, 0.013, 0.025 µg/mL [1]. In Vivo Carumonam disodium (1.31-6.89 mmol/kg; i.p.) induces seizures in DBA/2, Swiss and C57 mice [2]. Animal Model: 16-24g, 42-48 days DBA/2; 18-28, 42-48 days Swiss and C57 mice[2] Dosage: 1.31-6.89 mmol/kg Administration: I.p. Result: Induced seizure in DBA/2, Swiss and C57 mice. References [1]. Imada A, et al. In vitro and in vivo antibacterial activities of carumonam (AMA-1080), a new N-sulfonated monocyclic beta-lactam antibiotic. Antimicrob Agents Chemother. 1985 May;27(5):821-7. [2]. De Sarro A, et al. Comparative epileptogenic properties of two monobactam derivatives in C57, Swiss and DBA/2 mice. J Antimicrob Chemother. 1996 Sep;38(3):475-84. Chemical & Physical Properties Density 2.1±0.1 g/cm3 Melting Point 250ºC (dec.)(lit.) Molecular Formula C12H14N6O10S2 Molecular Weight 466.404 Exact Mass 466.021271 PSA 295.73000 LogP -2.26 Index of Refraction 1.820 InChIKey BGGXRVPCJUKHTQ-REOVRMSNSA-L SMILES NC(=O)OCC1C(NC(=O)C(=NOCC(=O)[O-])c2csc(N)n2)C(=O)N1S(=O)(=O)[O-].[Na+].[Na+]
Use ofCarumonam disodium is a potent antibiotic. Carumonam disodium shows antibacterial activity. Carumonam disodium induces seizure[1][2]. Areas >> Infection Research Areas >> Neurological Disease Signaling Pathways >> Anti-infection >> Bacterial In Vitro Carumonam disodium (0-100 µg/mL) exhibits antibacterial activity against Escherichia coli (cefazolin sensitive), Escherichia coli (cefazolin resistant), Klebsiella pneumoniae (cefazolin sensitive), Klebsiella pneumoniae (cefazolin) resistant), Klebsiella oxytoca, Enterobacter cloacae, Serratia marcescens (gentamicin sensitive), Serratia marcescens (gentamicin resistant), Proteus vulgaris, Proteus mirabilis, Proteus morganii, Proteus rettgeri, Proteus inconstans have MIC90 values of 0.2, 3.13, 0.2, respectively. 0.39, 0.2, 6.25, 0.2, 3.13, 0.05, 0.025, 0.78, 0.013, 0.025 µg/mL[1]. References [1]. Imada A, et al. In vitro and in vivo antibacterial activities of carumonam (AMA-1080), a new N-sulfonated monocyclic beta-lactam antibiotic. Antimicrob Agents Chemother. 1985 May;27(5):821-7. Chemical & Physical Properties Molecular Formula C12H14N6O10S2 Exact Mass 466.021271 PSA 295.73000 LogP -2.26 Index of Refraction 1.820 InChIKey BGGXRVPCJUKHTQ-REOVRMSNSA-L
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