CAS Number841205-47-8
SynonymsGTx-024; (2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide; UNII-O3571H3R8N; Ostarine; MK-2866; MK-2286
Molecular FormulaC19H14F3N3O3
Molecular Weight389.328
Purity98%%
Density1.4±0.1 g/cm3
Boiling Point632.3±55.0 °C at 760 mmHg
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 841205-47-8 |
| Catalog No. | 2A-1171184 |
| Chinese Name | (S)-N-(4-氰基-3-(三氟甲基)苯基)-3-(4-氰基苯氧基)-2-羟基-2-甲基丙酰胺 |
| Synonyms | GTx-024; (2S)-3-(4-Cyanophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide; UNII-O3571H3R8N; Ostarine; MK-2866; MK-2286 |
| Molecular Formula | C19H14F3N3O3 |
| Molecular Weight | 389.328 |
| Purity | 98% |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 632.3±55.0 °C at 760 mmHg |
| Storage Condition | -20°C, inert gas atmosphere |
| Application | Ostarine (MK-2866; GTX-024) is a selective androgen receptor modulator with an ED50 of 0.44 mg/day. |
| PubChem ID | 16416756 |
| SMILES | CC(O)(COc1ccc(C#N)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 |
| InChI | InChI=1S/C19H14F3N3O3/c1-18(27,11-28-15-6-2-12(9-23)3-7-15)17(26)25-14-5-4-13(10-24)16(8-14)19(20,21)22/h2-8,27H,11H2,1H3,(H,25,26)/t18-/m0/s1 |
| InChI Key | JNGVJMBLXIUVRD-SFHVURJKSA-N |
| Hazard Symbols | transportation |
| Bioactivity | Ostarine(MK-2866; GTX-024) is a modulator of human androgen receptor.IC50 value:Target: androgen receptorOstarine (MK-2866) is an androgen receptor modulator (SARM) with an ED50 of 0.44 mg/day. Ostarine (MK-2866) has anabolic activity. Lack of PSA increases in men and hair growth in women further corroborated selective anabolic effects of Ostarine (MK-2866). Ostarine (MK-2866) also resulted in a dose-dependent decrease in LDL and HDL cholesterol levels, with the average LDL/HDL ratio for all doses remaining in the low cardiovascular risk catergory. Related Catalog Signaling Pathways >> Others >> Androgen Receptor Research Areas >> Cancer References [1]. Thevis M, et al. Trafficking of drug candidates relevant for sports drug testing: detection of non-approved therapeutics categorized as anabolic and gene doping agents in products distributed via the Internet.Drug Test Anal. 2011 May;3(5):331-6. doi: 10.1002/dta.283. [2]. Zilbermint MF, et al. Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia. Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 632.3±55.0 °C at 760 mmHg Molecular Formula C19H14F3N3O3 Molecular Weight 389.328 Flash Point 336.2±31.5 °C Exact Mass 389.098724 PSA 106.14000 LogP 4.83 Vapour Pressure 0.0±2.0 mmHg at 25°C Index of Refraction 1.578 InChIKey JNGVJMBLXIUVRD-SFHVURJKSA-N SMILES CC(O)(COc1ccc(C#N)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 |
| Use of | Properties Name Enobosarm Synonym More Synonyms Ostarine Biological Activity Related Catalog Signaling Pathways >> Others >> Androgen Receptor Research Areas >> Cancer References [2]. Zilbermint MF, et al. Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia. Nonsteroidal selective androgen receptor modulator Ostarine in cancer cachexia. Chemical & Physical Properties Molecular Formula C19H14F3N3O3 Exact Mass 389.098724 PSA 106.14000 Index of Refraction 1.578 InChIKey JNGVJMBLXIUVRD-SFHVURJKSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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