CAS Number259793-96-9
Synonyms6-fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide; 2-Pyrazinecarboxamide,6-fluoro-3-hydroxy; T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide; 6-Fluoro-3-oxo-3,4-dihydro-2-pyrazinecarboxamide; Avigan; 6-Fluoro-3-hydroxypyrazine-2-carboxamide; favipiravir; UNII-EW5GL2X7E0
Molecular FormulaC5H4FN3O2
Molecular Weight157.103
Purity98%%
Density1.6±0.1 g/cm3
Boiling Point552.6±50.0 °C at 760 mmHg
Melting Point192 °C
AppearanceSolid;White to Almost white powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 259793-96-9 |
| Catalog No. | 2A-1171162 |
| Chinese Name | 法匹拉韦 |
| Synonyms | 6-fluoro-3-oxo-3,4-dihydropyrazine-2-carboxamide; 2-Pyrazinecarboxamide,6-fluoro-3-hydroxy; T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide; 6-Fluoro-3-oxo-3,4-dihydro-2-pyrazinecarboxamide; Avigan; 6-Fluoro-3-hydroxypyrazine-2-carboxamide; favipiravir; UNII-EW5GL2X7E0 |
| Molecular Formula | C5H4FN3O2 |
| Molecular Weight | 157.103 |
| Purity | 98% |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 552.6±50.0 °C at 760 mmHg |
| Melting Point | 192 °C |
| Appearance | Solid;White to Almost white powder to crystal |
| Water Solubility | Water solubility: Practically insoluble; Slightly |
| Storage Condition | 0-10°C; store in inert gas; avoid air, heat |
| Application | Favipiravir is a viral RNA polymerase inhibitor that converts to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits influenza virus RNA-dependent RNA polymerase |
| HTC | 2934999090 |
| PubChem ID | 652965 |
| SMILES | NC(=O)c1nc(F)c[nH]c1=O |
| InChI | InChI=1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11) |
| InChI Key | ZCGNOVWYSGBHAU-UHFFFAOYSA-N |
| Use of | Favipiravir is a novel viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with IC50 of 341 nM. Properties Name 5-fluoro-2-oxo-1H-pyrazine-3-carboxamide Synonym More Synonyms Favipiravir Biological Activity Description Favipiravir is a novel viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with IC50 of 341 nM. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Research Areas >> Infection IC50: 341 nM (RdRP)[1] References [1]. Furuta Y, et al. Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Res. 2013 Nov;100(2):446-54. [2]. Rocha-Pereira J, et al. Favipiravir (T-705) inhibits in vitro norovirus replication. Biochem Biophys Res Commun. 2012 Aug 10;424(4):777-80. Chemical & Physical Properties Molecular Formula C5H4FN3O2 Exact Mass 157.028748 PSA 88.84000 Index of Refraction 1.600 InChIKey ZCGNOVWYSGBHAU-UHFFFAOYSA-N SMILES NC(=O)c1nc(F)c[nH]c1=O Safety Information HS Code 2934999090 Synthetic Route 2-Pyrazinecarbo... 1137606-74-6 Favipiravir 259793-96-9 2-Pyrazinecarbo... 356783-31-8 Favipiravir 259793-96-9 3-hydroxypyrazi... 55321-99-8 Favipiravir 259793-96-9 Precursor & DownStream Precursor 6 CAS#:356783-31-8 2-Pyrazinecarbo... CAS#:55321-99-8 3-hydroxypyrazi... CAS#:356783-27-2 methyl 6-fluoro... CAS#:356783-42-1 Pyrazinecarboxa... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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