Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > 2-PropenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[3-Methyl-3-(4-Methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-, 4-Methylbenzenesulfonate (1:2)

2-PropenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[3-Methyl-3-(4-Methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-, 4-Methylbenzenesulfonate (1:2)

Name: 2-PropenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[3-Methyl-3-(4-Methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-, 4-Methylbenzenesulfonate (1:2)
Brand: 2A Biotech
SKU: 2A-1170975

CAS Number451493-31-5

Synonymsunii-z541vw0w40; av412; mp-412; AV-412 Tosylate; AV-412

Molecular FormulaC41H44ClFN6O7S2

Molecular Weight851.40500

Purity98%%

MSDSChinese English

Cat. No.: 2A-1170975 Purity: 98%%

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Quality Control of [ 451493-31-5 ] Purity: 98%% SDS Specification MoL

Chemical & Physical Properties
CAS Number	451493-31-5
Catalog No.	2A-1170975
Chinese Name	AV-412
Synonyms	unii-z541vw0w40; av412; mp-412; AV-412 Tosylate; AV-412
Molecular Formula	C41H44ClFN6O7S2
Molecular Weight	851.40500
Purity	98%
Storage Condition	2-8℃
Application	AV-412 (MP412) is an EGFR inhibitor. The IC50 values for inhibiting EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2 are 0.75, 0.5, 0.79, 2.3, and 19 nM respectively.
SMILES	C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1C#CC(C)(C)N1CCN(C)CC1.Cc1ccc(S(=O)(=O)O)cc1.Cc1ccc(S(=O)(=O)O)cc1
InChI Key	GTWJVFFZCKODEV-UHFFFAOYSA-N
Transport Info	Product name: AV-412

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2-PropenaMide, N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[3-Methyl-3-(4-Methyl-1-piperazinyl)-1-butyn-1-yl]-6-quinazolinyl]-, 4-Methylbenzenesulfonate (1:2)

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