
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 491833-30-8 |
| Catalog No. | 2A-1170946 |
| Chinese Name | N-[(1R,2R)-1-(2,3-二氢苯并[B][1,4]二恶英-6-基)-1-羟基-3-(吡咯烷-1-基)丙-2-基]壬酰胺 |
| Synonyms | N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]nonanamide; Genz-123346 (free base) |
| Molecular Formula | C24H38N2O4 |
| Molecular Weight | 418.569 |
| Purity | 98% |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 623.9±55.0 °C at 760 mmHg |
| Storage Condition | 2-8℃ |
| Application | Genz-123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1; the IC50 value for inhibiting GM1 is 14 nM. |
| PubChem ID | 46524645 |
| SMILES | CCCCCCCCC(=O)NC(CN1CCCC1)C(O)c1ccc2c(c1)OCCO2 |
| InChI | InChI=1S/C24H38N2O4/c1-2-3-4-5-6-7-10-23(27)25-20(18-26-13-8-9-14-26)24(28)19-11-12-21-22(17-19)30-16-15-29-21/h11-12,17,20,24,28H,2-10,13-16,18H2,1H3,(H,25,27)/t20-,24-/m1/s1 |
| InChI Key | JMNXWOFCUJJYEO-HYBUGGRVSA-N |
| Transport Info | Product name: Genz-123346(free base) |
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