| Chemical & Physical Properties | |
|---|---|
| CAS Number | 848942-61-0 |
| Catalog No. | 2A-1170826 |
| Chinese Name | AZD 8931 |
| Synonyms | AZD 8931; Sapitinib; Sapitinibum; S2192_Selleck; AZD8931 |
| Molecular Formula | C23H25ClFN5O3 |
| Molecular Weight | 473.928 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 632.8±55.0 °C at 760 mmHg |
| Storage Condition | -20°C |
| Application | Sapitinib (AZD-8931) is a reversible, ATP-competitive EGFR inhibitor with IC50 values of 4, 3 and 4 nM for EGFR, ErbB2 and ErbB3, respectively. |
| PubChem ID | 16590003 |
| SMILES | CNC(=O)CN1CCC(Oc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC)CC1 |
| InChI | InChI=1S/C23H25ClFN5O3/c1-26-21(31)12-30-8-6-14(7-9-30)33-20-10-15-18(11-19(20)32-2)27-13-28-23(15)29-17-5-3-4-16(24)22(17)25/h3-5,10-11,13-14H,6-9,12H2,1-2H3,(H,26,31)(H,27,28,29) |
| InChI Key | DFJSJLGUIXFDJP-UHFFFAOYSA-N |
| Transport Info | Product Name: Sapitinib |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| D-Amino acids | 2A-1170820 | 2A-1170820 |
| LY2940680 | 1258861-20-9 | 2A-1170821 |
| Erteberel (LY500307) | 533884-09-2 | 2A-1170822 |
| LY-2608204 | 1234703-40-2 | 2A-1170823 |
| NVP-BHG712 | 940310-85-0 | 2A-1170825 |
| ABT-199 | 1257044-40-8 | 2A-1170828 |
| XL-647 | 781613-23-8 | 2A-1170830 |
| 2,2-DIPHENYL-N-(2,2,2-TRICHLORO-1-[3-(4-FLUORO-3-NITROPHENYL)THIOUREIDO]ETHYL)ACETAMIDE | 905973-89-9 | 2A-1170831 |
| Belinostat (PXD101) | 414864-00-9 | 2A-1170832 |
| XL647 4-methylbenzenesulfonate | 1000599-06-3 | 2A-1170834 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS