CAS Number887375-67-9
Synonyms4-Fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline hydrochloride dihydrate; RIPASUDIL HYDROCHLORIDE DIHYDRATE; (S)-4-Fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline hydrochloride dihydrate; Ripasudil free base; K-115; Ripasudil
Molecular FormulaC15H23ClFN3O4S
Molecular Weight395.877
Purity98.00%
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 887375-67-9 |
| Catalog No. | 2A-1170594 |
| Chinese Name | 盐酸瑞舒地尔 |
| Synonyms | 4-Fluoro-5-{[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl}isoquinoline hydrochloride dihydrate; RIPASUDIL HYDROCHLORIDE DIHYDRATE; (S)-4-Fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline hydrochloride dihydrate; Ripasudil free base; K-115; Ripasudil |
| Molecular Formula | C15H23ClFN3O4S |
| Molecular Weight | 395.877 |
| Purity | 98.00 |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Ripasudil (K-115) is a specific inhibitor of ROCK that inhibits the activities of ROCK2 and ROCK1 with IC50 values of 19 and 51 nM respectively. |
| PubChem ID | 16728427 |
| SMILES | CC1CNCCCN1S(=O)(=O)c1cccc2cncc(F)c12.Cl.O.O |
| InChI | InChI=1S/C15H18FN3O2S.ClH.2H2O/c1-11-8-17-6-3-7-19(11)22(20,21)14-5-2-4-12-9-18-10-13(16)15(12)14;;;/h2,4-5,9-11,17H,3,6-8H2,1H3;1H;2*1H2/t11-;;;/m0.../s1 |
| InChI Key | CMDJNMACGABCKQ-XVSRHIFFSA-N |
| Transport Info | Product name: Ripasilidil dihydrate (K-115) hydrochloride |
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